ORIGINAL ARTICLE An assessment of the safety, hemodynamic response, and diagnostic accuracy of commonly used vasodilator stressors in patients with severe aortic stenosis a a a Nasir Hussain, MD, Waseem Chaudhry, MD, Alan W. Ahlberg, MA, b a c Richard S. Amara, MD, Ahmed Elfar, MD, Matthew W. Parker, MD, d b d John A. Savino III, MD, Ruwanthi Titano, MD, Milena J. Henzlova, MD, PhD, and William L. Duvall, MD Division of Cardiology, Hartford Hospital, Hartford, CT Department of Medicine, Mount Sinai Hospital, New York, NY Division of Cardiovascular Medicine, University of Massachusetts Medical Center, Worcester, MA Mount Sinai Heart, Mount Sinai Hospital, New York, NY Received Nov 9, 2015; accepted Jan 21, 2016 doi:10.1007/s12350-016-0427-1 Background. Increasing numbers of patients are undergoing transcatheter aortic valve replacement, which often involves assessment of coronary artery disease ischemic burden. The safety and diagnostic accuracy of vasodilator stress agents in patients with severe aortic stenosis (AS) undergoing SPECT myocardial perfusion imaging (MPI) has not been established. Methods. Patients with severe AS (valve area <1 cm ) on echocardiography who underwent vasodilator stress SPECT MPI at two centers were identiﬁed. Patients with aortic valve intervention prior to MPI or who underwent concurrent exercise
Journal of Nuclear Cardiology – Springer Journals
Published: Mar 15, 2016
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