Drug Saf (2017) 40:799–808 DOI 10.1007/s40264-017-0550-1 OR IGINAL RESEARCH ARTIC L E An Algorithm to Identify Generic Drugs in the FDA Adverse Event Reporting System 1 2,3 2,4,5 6 • • • Geetha Iyer Sathiya Priya Marimuthu Jodi B. Segal Sonal Singh Published online: 7 June 2017 Springer International Publishing Switzerland 2017 Abstract number/abbreviated NDA (ANDA), and speciﬁc use of the Introduction Although generic drugs constitute approxi- term ‘generic’ or ‘brand’ to classify the focal drug of each mately 88% of drugs prescribed in the US, there are no case report as deﬁnitely generic (two of three criteria), reliable methods to identify generic drugs in the US FDA probably generic (one of three criteria), brand, and cannot Adverse Event Reporting System (FAERS). be assessed. Inter-rater reliability was estimated using Objective The aim of this study was to develop an algo- kappa coefﬁcients, and internal consistency was estimated rithm for identifying generic drugs in the FAERS. using Cronbach’s alpha. We compared the classiﬁcation of Data Source We used 1237 adverse event reports for the drugs as generic versus non-generic in publicly avail- tamsulosin, levothyroxine, and amphetamine/dextroam- able FAERS compared with the original case reports phetamine from the publicly available FAERS
Drug Safety – Springer Journals
Published: Jun 7, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera