Reactions 1704, p29 - 2 Jun 2018
Serotonin syndrome: case report
A female patient [age not stated] developed serotonin
syndrome following treatment with amitriptyline.
In 2008, the female patient was taken to the emergency
room in the presence of police following the administration of
amitriptyline in high doses [dosage, route and indication not
stated]. Subsequently, she was hospitalised. The current
hospitalisation was her fourth hospital admission. She was first
hospitalised in 2004 following a suicide attempt with
unspecified antidepressant drugs. During her subsequent
hospitalisations, she was treated for depression. At the time of
her current admission, she appeared anxious, agitated, tense,
disoriented in time, fearful and had tremor, incoherent speech
and hyper-reflexia. Initially, both medication-induced delirium
and serotonin syndrome were considered. Later, her
underlying condition was diagnosed as bipolar affective
disorder, and it was considered that the symptoms of
serotonin syndrome interfered with the diagnosis of bipolar
affective disorder [duration of treatment to reaction onset and
outcome not stated].
Author comment: "Serotonin syndrome is an iatrogenic
disorder. . .This case report is presented to show how the
serotonin syndrome symptoms interfere with the signs and
symptoms of other psychiatric disorders".
Milovac Z, et al. Diagnostic dilemma - Serotonin syndrome or medication induced
delirium: Case report. [Serbian]. Socijalna Psihijatrija 38: 80-84, No. 1, Mar 2010.
Available from: URL: http://psihijatrija.hr/soc_psih_sazetak_v38_1_201003.htm
[Serbian; summarised from an English abstract] - Croatia
Reactions 2 Jun 2018 No. 17040114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved