Purpose of Review Breast cancer is the most common cancer diagnosed among US women. Air pollution is a pervasive mixture of chemicals containing carcinogenic compounds and chemicals with endocrine-disrupting properties. In the present review, we examine the epidemiologic evidence regarding the association between air pollution measures and breast cancer risk. Recent Findings We identified 17 studies evaluating the risk of breast cancer associated with air pollution. A higher risk of breast cancer has been associated with nitrogen dioxide (NO ) and nitrogen oxide (NO ) levels, both of which are proxies for traffic 2 x exposure. However, there is little evidence supporting a relationship for measures of traffic count or distance to nearest road, or for measures of particulate matter (PM), except potentially for nickel and vanadium, which are components of PM . Hazardous air toxic levels and sources of indoor air pollution may also contribute to breast cancer risk. There is little existing evidence to support that the relationship between air pollution and breast cancer risk varies by either menopausal status at diagnosis or combined tumor hormone receptor subtype defined by the estrogen receptor (ER) and progesterone receptor (PR). Summary Epidemiologic evidence to date suggests an association between
Current Epidemiology Reports – Springer Journals
Published: Mar 27, 2018
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