Aggressive angiomyxoma of the liver: a case report and literature review

Aggressive angiomyxoma of the liver: a case report and literature review Background: Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor that occurs almost exclusively in the soft tissue of the pelvis and perineum. AAM has both locally infiltrative and recurrent characteristics. Very few cases of AAM occurring outside of the pelvis and perineum have been reported. Here, we report a case of AAM originating in the liver of a 33-year-old female patient. Case presentation: A 33-year-old woman underwent S8 subsegmentectomy after clinical diagnosis of a mucinous cystic neoplasm of the liver. Histological analysis revealed a tumor composed of spindle-shaped cells with vascular proliferation in a myxoid stroma. Immunohistochemically, the tumor cells stained positively for CD34, estrogen receptor (ER), and progesterone receptor (PgR) and negatively for S-100, EMA, CK19, CD99, HMB45, and α-smooth muscle actin. The tumor was diagnosed as AAM originating from the liver. The patient received no adjuvant chemotherapy. No sign of recurrence or distant metastasis has been noted for 10 months after the surgery. Conclusions: We here report a second case of AAM originating from the liver, which is an uncommon location for this particular tumor. Keywords: Aggressive angiomyxoma (AAM), Liver, Immunohistochemistry Background report describes an additional case of primary AAM Aggressive angiomyxoma (AAM) is a rare mesenchymal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Surgical Case Reports Springer Journals

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by The Author(s).
Subject
Medicine & Public Health; Surgery
eISSN
2198-7793
D.O.I.
10.1186/s40792-017-0365-4
Publisher site
See Article on Publisher Site

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