Adrenal Vein Sampling for Primary Aldosteronism: A 2-Week Protocol for Withdrawal of Renin-Stimulating Antihypertensives

Adrenal Vein Sampling for Primary Aldosteronism: A 2-Week Protocol for Withdrawal of... Cardiovasc Intervent Radiol (2017) 40:1367–1371 DOI 10.1007/s00270-017-1637-x CLINICAL INVESTIGATI O N V ENOUS I NT ERVENTIONS Adrenal Vein Sampling for Primary Aldosteronism: A 2-Week Protocol for Withdrawal of Renin-Stimulating Antihypertensives 1 2 3 4 • • • Kevin C. Ching Debbie L. Cohen Douglas L. Fraker Scott O. Trerotola Received: 12 January 2017 / Accepted: 22 March 2017 / Published online: 4 April 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2017 Abstract Measurements Plasma renin activity (PRA) was measured Objective For evaluation of primary aldosteronism, inter- immediately before venous sampling to assess for renin national guidelines recommend a 4–6 week withdrawal of suppression (PRA \ 0.5 ng/ml/hr). Demographics, anti- spironolactone, eplerenone, and amiloride prior to adrenal hypertensive medications, plasma aldosterone, plasma vein sampling (AVS). It is not always feasible to withdraw renin activity, and outcomes were reviewed. these drugs in patients with severe hypertension and hypo- Results 100% of procedures were diagnostic (selectivity kalemia. We present our experience evaluating the efficacy index C 3) and lateralization (lateralization index C 4) and clinical outcomes of a 2-week protocol for withdrawal of was confirmed in 22/32 patients. 19/32 patients had con- renin-stimulating http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png CardioVascular and Interventional Radiology Springer Journals

Adrenal Vein Sampling for Primary Aldosteronism: A 2-Week Protocol for Withdrawal of Renin-Stimulating Antihypertensives

Loading next page...
 
/lp/springer_journal/adrenal-vein-sampling-for-primary-aldosteronism-a-2-week-protocol-for-0N5FyCpiG4
Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE)
Subject
Medicine & Public Health; Imaging / Radiology; Cardiology; Nuclear Medicine; Ultrasound
ISSN
0174-1551
eISSN
1432-086X
D.O.I.
10.1007/s00270-017-1637-x
Publisher site
See Article on Publisher Site

Abstract

Cardiovasc Intervent Radiol (2017) 40:1367–1371 DOI 10.1007/s00270-017-1637-x CLINICAL INVESTIGATI O N V ENOUS I NT ERVENTIONS Adrenal Vein Sampling for Primary Aldosteronism: A 2-Week Protocol for Withdrawal of Renin-Stimulating Antihypertensives 1 2 3 4 • • • Kevin C. Ching Debbie L. Cohen Douglas L. Fraker Scott O. Trerotola Received: 12 January 2017 / Accepted: 22 March 2017 / Published online: 4 April 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2017 Abstract Measurements Plasma renin activity (PRA) was measured Objective For evaluation of primary aldosteronism, inter- immediately before venous sampling to assess for renin national guidelines recommend a 4–6 week withdrawal of suppression (PRA \ 0.5 ng/ml/hr). Demographics, anti- spironolactone, eplerenone, and amiloride prior to adrenal hypertensive medications, plasma aldosterone, plasma vein sampling (AVS). It is not always feasible to withdraw renin activity, and outcomes were reviewed. these drugs in patients with severe hypertension and hypo- Results 100% of procedures were diagnostic (selectivity kalemia. We present our experience evaluating the efficacy index C 3) and lateralization (lateralization index C 4) and clinical outcomes of a 2-week protocol for withdrawal of was confirmed in 22/32 patients. 19/32 patients had con- renin-stimulating

Journal

CardioVascular and Interventional RadiologySpringer Journals

Published: Apr 4, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off