Adefovir/entecavir

Adefovir/entecavir Reactions 1680, p19 - 2 Dec 2017 Creatine kinase increased: case report A real-world retrospective clinical study described a patient [age and sex not stated], who showed increased creatine kinase during the two-year combination therapy treatment with adefovir and entecavir for chronic hepatitis B [route, dosage, duration of treatment to reaction onset and outcome not stated]. Author comment: "After a detailed evaluation, only 14 patients with CK elevations should be considered indicative of drug-related side effects, [. . .] 1 patient in entecavir + adefovir". Wang M-L, et al. Efficacy and safety of three adefovir-based combination therapies in HBeAg-positive chronic hepatitis B patients with suboptimal response to adefovir monotherapy. Journal of Viral Hepatitis 24 (Suppl. 1): 21-28, Nov 2017. Available from: URL: http://doi.org/10.1111/jvh.12792 - China 803286288 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Adefovir/entecavir

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-38950-4
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p19 - 2 Dec 2017 Creatine kinase increased: case report A real-world retrospective clinical study described a patient [age and sex not stated], who showed increased creatine kinase during the two-year combination therapy treatment with adefovir and entecavir for chronic hepatitis B [route, dosage, duration of treatment to reaction onset and outcome not stated]. Author comment: "After a detailed evaluation, only 14 patients with CK elevations should be considered indicative of drug-related side effects, [. . .] 1 patient in entecavir + adefovir". Wang M-L, et al. Efficacy and safety of three adefovir-based combination therapies in HBeAg-positive chronic hepatitis B patients with suboptimal response to adefovir monotherapy. Journal of Viral Hepatitis 24 (Suppl. 1): 21-28, Nov 2017. Available from: URL: http://doi.org/10.1111/jvh.12792 - China 803286288 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

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