Addendum: Application of bio-orthogonal
proteome labeling to cell transplantation and
, Michael J. Conboy
, Melod Mehdipour
, Yutong Liu
, Thanhtra P. Tran
, Aaron Blotnick
, Thalie Cavalcante Santos
& Irina M. Conboy
Addendum to: Nature Communications https://doi.org/10.1038/s41467-017-00698-y, published online 21 September 2017
We would like to make our readers aware of the publication by Alvarez-Castelao et al., which reports the original development of the
Floxed MetRS L274G mice for the cell-speciﬁc labelling of proteins in vivo and provides an in-depth characterisation of these mice
Breeding pairs of Floxed mice were graciously donated by Erin Schuman and coworkers well in advance of the publication by Alvarez-
Castelao et al. Application of this technology to cell transplantation, selective identiﬁcation of ‘young’ proteins in the setting of
heterochronic parabiosis, and array proteomics was developed by the Conboy laboratory.
1. Alvarez-Castelao, B. et al Cell-type speciﬁc metabolic labelling of nascent proteomes in vivo. Nat. Biotech. 35, 1196–1201 (2017).
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© The Author(s) 2018
Department of Bioengineering, UC Berkeley and QB3 Institutes, Berkeley, CA 94709, USA.
Present address: The 7th afﬁliated hospital of Sun Yat-Sen
University, ShenZhen, Guandong 510275, China. Correspondence and requests for materials should be addressed to I.M.C. (email: firstname.lastname@example.org)