Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Acute kidney injury is associated with subsequentinfection in neonates after the Norwood procedure: a retrospective chart review

Acute kidney injury is associated with subsequentinfection in neonates after the Norwood... Background Acute kidney injury (AKI) and infection are common complications after pediatric cardiac surgery. No pediatric study has evaluated for an association between postoperative AKI and infection. The objective of this study was to determine if AKI in neonates after cardiopulmonary bypass was associated with the development of a postoperative infection. Methods We performed a single center retrospective chart review from January 2009 to December 2015 of neonates (age ≤ 30 days) undergoing the Norwood procedure. AKI was defined by the modified neonatal Kidney Disease Improving Global outcomes serum creatinine criteria using (1) measured serum creatinine and (2) creatinine corrected for fluid balance on postoperative days 1–4. Infection, (culture positive or presumed), must have occurred after a diagnosis of AKI and within 60 days of surgery. Results Ninety-five patients were included, of which postoperative infection occurred in 42 (44%). AKI occurred in 38 (40%) and 42 (44%) patients by measured serum creatinine and fluid overload corrected creatinine, respectively, and was most commonly diagnosed on postoperative day 2. The median time to infection from the time of surgery and AKI was 7 days (IQR 5–14 days) and 6 days (IQR 3–13 days), respectively. After adjusting for confounders, the odds of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Nephrology Springer Journals

Acute kidney injury is associated with subsequentinfection in neonates after the Norwood procedure: a retrospective chart review

Download PDF
8 pages
Read Article

Loading next page...
 
/lp/springer_journal/acute-kidney-injury-is-associated-with-subsequentinfection-in-neonates-hih0HORFCN
Publisher
Springer Journals
Copyright
Copyright © 2018 by IPNA
Subject
Medicine & Public Health; Pediatrics; Nephrology; Urology
ISSN
0931-041X
eISSN
1432-198X
DOI
10.1007/s00467-018-3907-5
Publisher site
See Article on Publisher Site

Abstract

Background Acute kidney injury (AKI) and infection are common complications after pediatric cardiac surgery. No pediatric study has evaluated for an association between postoperative AKI and infection. The objective of this study was to determine if AKI in neonates after cardiopulmonary bypass was associated with the development of a postoperative infection. Methods We performed a single center retrospective chart review from January 2009 to December 2015 of neonates (age ≤ 30 days) undergoing the Norwood procedure. AKI was defined by the modified neonatal Kidney Disease Improving Global outcomes serum creatinine criteria using (1) measured serum creatinine and (2) creatinine corrected for fluid balance on postoperative days 1–4. Infection, (culture positive or presumed), must have occurred after a diagnosis of AKI and within 60 days of surgery. Results Ninety-five patients were included, of which postoperative infection occurred in 42 (44%). AKI occurred in 38 (40%) and 42 (44%) patients by measured serum creatinine and fluid overload corrected creatinine, respectively, and was most commonly diagnosed on postoperative day 2. The median time to infection from the time of surgery and AKI was 7 days (IQR 5–14 days) and 6 days (IQR 3–13 days), respectively. After adjusting for confounders, the odds of

Journal

Pediatric Nephrology – Springer Journals

Published: Mar 5, 2018

References

  • Cause of death in acute renal failure
    Woodrow, G; Turney, JH
  • Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group
    Liano, F; Pascual, J
  • Acute renal failure: clinical outcome and causes of death
    Barretti, P; Soares, VA
  • Defining the cause of death in hospitalised patients with acute kidney injury
    Selby, NM; Kolhe, NV; CW, MI; Monaghan, J; Lawson, N; Elliott, D; Packington, R; Fluck, RJ
  • Early acute kidney injury and sepsis: a multicentre evaluation
    Bagshaw, SM; George, C; Bellomo, R
  • Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes
    Bagshaw, SM; Uchino, S; Bellomo, R; Morimatsu, H; Morgera, S; Schetz, M; Tan, I; Bouman, C; Macedo, E; Gibney, N; Tolwani, A; Oudemans-van Straaten, HM; Ronco, C; Kellum, JA
  • Analysis of progression in risk, injury, failure, loss, and end-stage renal disease classification on outcome in patients with severe sepsis and septic shock
    Kim, WY; Huh, JW; Lim, CM; Koh, Y; Hong, SB
  • Prospective multicenter study on epidemiology of acute kidney injury in the ICU: a critical care nephrology Italian collaborative effort (NEFROINT)
    Piccinni, P; Cruz, DN; Gramaticopolo, S; Garzotto, F; Dal Santo, M; Aneloni, G; Rocco, M; Alessandri, E; Giunta, F; Michetti, V; Iannuzzi, M; Belluomo Anello, C; Brienza, N; Carlini, M; Pelaia, P; Gabbanelli, V; Ronco, C
  • Acute kidney injury in patients with severe sepsis in Finnish Intensive Care Units
    Poukkanen, M; Vaara, ST; Pettila, V; Kaukonen, KM; Korhonen, AM; Hovilehto, S; Inkinen, O; Laru-Sompa, R; Kaminski, T; Reinikainen, M; Lund, V; Karlsson, S
  • Renal involvement in sepsis: a prospective single-center study of 136 cases
    Shah, PR; Gireesh, MS; Kute, VB; Vanikar, AV; Gumber, MR; Patel, HV; Goplani, KR; Trivedi, HL
  • Severe infection, sepsis and acute kidney injury
    Vandijck, DM; Reynvoet, E; Blot, SI; Vandecasteele, E; Hoste, EA
  • An analysis of clinical characteristics of septic acute kidney injury by using criteria of Kidney Disease: Improving Global Outcomes
    Zang, ZD; Yan, J
  • Analysis of the characteristics of patients suffering from acute kidney injury following severe trauma receiving renal replacement therapy
    Zhu, J; Zhang, M
  • The effect of acute renal failure on mortality. A cohort analysis
    Levy, EM; Viscoli, CM; Horwitz, RI
  • Renal dysfunction and serious infections after open-heart surgery
    Thakar, CV; Yared, JP; Worley, S; Cotman, K; Paganini, EP
  • Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy
    Hoste, EA; Blot, SI; Lameire, NH; Vanholder, RC; Bacquer, D; Colardyn, FA
  • Epidemiology of infection in critically ill patients with acute renal failure
    Reynvoet, E; Vandijck, DM; Blot, SI; Dhondt, AW; Waele, JJ; Claus, S; Buyle, FM; Vanholder, RC; Hoste, EA
  • Sepsis as a cause and consequence of acute kidney injury: Program to Improve Care in Acute Renal Disease
    Mehta, RL; Bouchard, J; Soroko, SB; Ikizler, TA; Paganini, EP; Chertow, GM; Himmelfarb, J
  • Risk of developing severe sepsis after acute kidney injury: a population-based cohort study
    Lai, TS; Wang, CY; Pan, SC; Huang, TM; Lin, MC; Lai, CF; Wu, CH; Wu, VC; Chien, KL
  • Acute renal failure in the patient undergoing cardiac operation. Prevalence, mortality rate, and main risk factors
    Zanardo, G; Michielon, P; Paccagnella, A; Rosi, P; Calo, M; Salandin, V; Ros, A; Michieletto, F; Simini, G
  • Acute renal failure associated with cardiac operations. A case-control study
    Corwin, HL; Sprague, SM; GA, DL; Norusis, MJ
  • Immediate consequences of acute kidney injury: the impact of traditional and nontraditional complications on mortality in acute kidney injury
    Faubel, S; Shah, PB
  • Impaired monocyte cytokine production in critically ill patients with acute renal failure
    Himmelfarb, J; Le, P; Klenzak, J; Freedman, S; McMenamin, ME; Ikizler, TA
  • Congenital heart surgery in infants: effects of acute kidney injury on outcomes
    Blinder, JJ; Goldstein, SL; Lee, VV; Baycroft, A; Fraser, CD; Nelson, D; Jefferies, JL
  • Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study
    Li, S; Krawczeski, CD; Zappitelli, M; Devarajan, P; Thiessen-Philbrook, H; Coca, SG; Kim, RW; Parikh, CR
  • Peritoneal dialysis vs furosemide for prevention of fluid overload in infants after cardiac surgery: a randomized clinical trial
    Kwiatkowski, DM; Goldstein, SL; Cooper, DS; Nelson, DP; Morales, DL; Krawczeski, CD
  • Acute kidney injury based on corrected serum creatinine is associated with increased morbidity in children following the arterial switch operation
    Basu, RK; Andrews, A; Krawczeski, C; Manning, P; Wheeler, DS; Goldstein, SL
  • Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients
    Macedo, E; Bouchard, J; Soroko, SH; Chertow, GM; Himmelfarb, J; Ikizler, TA; Paganini, EP; Mehta, RL
  • Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes
    Liu, KD; Thompson, BT; Ancukiewicz, M; Steingrub, JS; Douglas, IS; Matthay, MA; Wright, P; Peterson, MW; Rock, P; Hyzy, RC; Anzueto, A; Truwit, JD
  • Comparison of shunt types in the Norwood procedure for single-ventricle lesions
    Ohye, RG; Sleeper, LA; Mahony, L; Newburger, JW; Pearson, GD; Lu, M; Goldberg, CS; Tabbutt, S; Frommelt, PC; Ghanayem, NS; Laussen, PC; Rhodes, JF; Lewis, AB; Mital, S; Ravishankar, C; Williams, IA; Dunbar-Masterson, C; Atz, AM; Colan, S; Minich, LL; Pizarro, C; Kanter, KR; Jaggers, J; Jacobs, JP; Krawczeski, CD; Pike, N; BW, MC; Virzi, L; Gaynor, JW
  • Stage I palliation for hypoplastic left heart syndrome: Norwood versus Sano modification
    Reemtsen, BL; Pike, NA; Starnes, VA
  • Risk factors for mortality after the Norwood procedure using right ventricle to pulmonary artery shunt
    Sano, S; Huang, SC; Kasahara, S; Yoshizumi, K; Kotani, Y; Ishino, K
  • Impact of preoperative risk factors on outcomes after Norwood palliation for hypoplastic left heart syndrome
    Shamszad, P; Gospin, TA; Hong, BJ; McKenzie, ED; Petit, CJ
  • Risk factors for hospital morbidity and mortality after the Norwood procedure: a report from the Pediatric Heart Network Single Ventricle Reconstruction trial
    Tabbutt, S; Ghanayem, N; Ravishankar, C; Sleeper, LA; Cooper, DS; Frank, DU; Lu, M; Pizarro, C; Frommelt, P; Goldberg, CS; Graham, EM; Krawczeski, CD; Lai, WW; Lewis, A; Kirsh, JA; Mahony, L; Ohye, RG; Simsic, J; Lodge, AJ; Spurrier, E; Stylianou, M; Laussen, P
  • Complications after the Norwood operation: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database
    Hornik, CP; He, X; Jacobs, JP; Li, JS; Jaquiss, RD; Jacobs, ML; O'Brien, SM; Peterson, ED; Pasquali, SK
  • The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study Group
    Liano, F; Junco, E; Pascual, J; Madero, R; Verde, E
  • Neonatal acute kidney injury
    Selewski, DT; Charlton, JR; Jetton, JG; Guillet, R; Mhanna, MJ; Askenazi, DJ; Kent, AL
  • Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support
    Harris, PA; Taylor, R; Thielke, R; Payne, J; Gonzalez, N; Conde, JG
  • Bedside prediction rule for infections after pediatric cardiac surgery
    Algra, SO; Driessen, MM; Schadenberg, AW; Schouten, AN; Haas, F; Bollen, CW; Houben, ML; Jansen, NJ
  • Major infection after pediatric cardiac surgery: a risk estimation model
    Barker, GM; O'Brien, SM; Welke, KF; Jacobs, ML; Jacobs, JP; Benjamin, DK; Peterson, ED; Jaggers, J; Li, JS
  • Major infection after pediatric cardiac surgery: external validation of risk estimation model
    Kansy, A; Jacobs, JP; Pastuszko, A; Mirkowicz-Malek, M; Manowska, M; Jezierska, E; Maruszewski, P; Burczynski, P; Maruszewski, B
  • Cumulative corticosteroid exposure and infection risk after complex pediatric cardiac surgery
    Mastropietro, CW; Barrett, R; Davalos, MC; Zidan, M; Valentine, KM; Delius, RE; Walters, HL
  • Renal systems biology of patients with systemic inflammatory response syndrome
    Tsalik, EL; Willig, LK; Rice, BJ; Velkinburgh, JC; Mohney, RP; McDunn, JE; Dinwiddie, DL; Miller, NA; Mayer, ES; Glickman, SW; Jaehne, AK; Glew, RH; Sopori, ML; Otero, RM; Harrod, KS; Cairns, CB; Fowler, VG; Rivers, EP; Woods, CW; Kingsmore, SF; Langley, RJ
  • Epidemiology of acute kidney injury in critically ill children and young adults
    Kaddourah, A; Basu, RK; Bagshaw, SM; Goldstein, SL

You’re reading a free preview. Subscribe to read the entire article.

Try 2 weeks free now

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

or browse the journals available

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$499/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

Sign up
for free
Start 14 day
Free Trial