Acute forearm compartment syndrome as first presentation of acquired haemophilia A with factor VIII inhibitor

Acute forearm compartment syndrome as first presentation of acquired haemophilia A with factor... Eur J Plast Surg (2013) 36:537–538 DOI 10.1007/s00238-013-0812-9 LETTER TO THE EDITOR Acute forearm compartment syndrome as first presentation of acquired haemophilia A with factor VIII inhibitor Theodore Nanidis & Pari-Naz Mohanna & David Ross Received: 14 January 2013 /Accepted: 4 February 2013 /Published online: 17 February 2013 Springer-Verlag Berlin Heidelberg 2013 Sir, (0.90–1.10); activated partial thromboplastin time (APTT), We present a case of spontaneous forearm compartment 2.10 (0.85–1.16); APTT 50/50 Correction, 1.26 (0.80–1.16) syndrome secondary to atraumatic bleeding as a first pre- and D-dimers, 0.59 (0.00–0.25). The finding of an elevated sentation of acquired haemophilia. This is a rare disorder APTT with poor correction on 50:50 mix suggested the with an estimated incidence of 1 per 1,000,000 per year and presence of a factor inhibitor. As haemophilia was sus- a mortality rate of up to 22 % [1]. There is only a single case pected, urgent haematology advice was sought, and detailed study in the literature reporting such an association [2]. We factor VIII, IX, XI, XII and vWF assays were sent. present a similar case of upper limb compartment syndrome The patient, however, deteriorated extremely rapidly dis- in a patient with undiagnosed acquired haemophilia requir- playing unequivocal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Acute forearm compartment syndrome as first presentation of acquired haemophilia A with factor VIII inhibitor

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2013 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Plastic Surgery
ISSN
0930-343X
eISSN
1435-0130
D.O.I.
10.1007/s00238-013-0812-9
Publisher site
See Article on Publisher Site

Abstract

Eur J Plast Surg (2013) 36:537–538 DOI 10.1007/s00238-013-0812-9 LETTER TO THE EDITOR Acute forearm compartment syndrome as first presentation of acquired haemophilia A with factor VIII inhibitor Theodore Nanidis & Pari-Naz Mohanna & David Ross Received: 14 January 2013 /Accepted: 4 February 2013 /Published online: 17 February 2013 Springer-Verlag Berlin Heidelberg 2013 Sir, (0.90–1.10); activated partial thromboplastin time (APTT), We present a case of spontaneous forearm compartment 2.10 (0.85–1.16); APTT 50/50 Correction, 1.26 (0.80–1.16) syndrome secondary to atraumatic bleeding as a first pre- and D-dimers, 0.59 (0.00–0.25). The finding of an elevated sentation of acquired haemophilia. This is a rare disorder APTT with poor correction on 50:50 mix suggested the with an estimated incidence of 1 per 1,000,000 per year and presence of a factor inhibitor. As haemophilia was sus- a mortality rate of up to 22 % [1]. There is only a single case pected, urgent haematology advice was sought, and detailed study in the literature reporting such an association [2]. We factor VIII, IX, XI, XII and vWF assays were sent. present a similar case of upper limb compartment syndrome The patient, however, deteriorated extremely rapidly dis- in a patient with undiagnosed acquired haemophilia requir- playing unequivocal

Journal

European Journal of Plastic SurgerySpringer Journals

Published: Aug 1, 2013

References

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