Hepatol Int (2017) 11 (Suppl 1):S1–S1093 DOI 10.1007/s12072-016-9783-9 AB STRACTS Abstracts of the 26th Annual Conference of APASL, February 15–19, 2017, Shanghai, China Asian Paciﬁc Association for the Study of the Liver 2017 achieved by 100% (7/7) of patients with prior PI failure; 100% (42/42) Plenary Presentation with HCV/HIV coinfection; 91% (63/69) with advanced ﬁbrosis (in- cludes 3 PI failures, 10 coinfections, 12 post-transplant); 90% (54/60) 17 February 2017 (Friday) with cirrhosis (includes 4 coinfections); 91% (20/22) post-liver trans- Plenary Presentation 01 plant, and 100% (125/125) with no/mild ﬁbrosis. By HCV genotype, 15:45–17:15 98% (49/50) with GT-1b, 93% (13/14) with GT-2, 94% (179/190) with GT-3, and a single patient with GT-6 achieved SVR. Baseline NS5A RAS were detected in 13% (33/257) of patients. SVR was achieved in 85% (28/33) of patients with NS5A RAS: 100% (6/6) GT-1b patients PL001 with L31 M or Y93H, 75% (3/4) GT-2 with L31 M, 82% (18/22) of GT- 3 with A30 K or Y93H (including all of 8 with no/mild ﬁbrosis), and in Impact of baseline NS5A polymorphisms on sustained virologic the single GT-6 patient with R30S. NS5A RAS were detected at relapse response rates to treatment with daclatasvir plus sofosbuvir in all
Hepatology International – Springer Journals
Published: Feb 2, 2017
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