ISSN 1062-3604, Russian Journal of Developmental Biology, 2006, Vol. 37, No. 4, pp. 259–266. © Pleiades Publishing, Inc., 2006. Original Russian Text © 2006, published in Ontogenez, 2006, Vol. 37, No. 4, pp. 311–320. Abstracts of Papers at the Conference of Young Scientists, Kol’tsov Institute of Developmental Biology of the Russian Academy of Sciences (December 21, 2005) DOI: 10.1134/S1062360406040102 Dynamics of Spontaneous Apoptosis and Proliferation in Immunocompetent Organs during Perinatal Development of Rats M. A. Afanasyeva and V. I. Melnikova Laboratory of Histogenesis Apoptosis, or programmed cell death, and prolifera- the highest on E18 (ca. 32%) and at this time, the spleen tion accompanied by the differentiation of immuno- is colonized by lymphocyte precursors. By the moment competent cells are two oppositely acting processes, of birth, their numbers decreased twice (17%). On P7, which determine the qualitative and quantitative com- when the spleen is colonized by T-lymphocytes from position of the population of lymphocytes. These pro- the thymus and hemopoietic precursors from the bone cesses play an especially important role during the marrow, the proliferative activity again increased up to immune system development. The aim of this work was 22% and then gradually decreased to 7% on P30. The
Russian Journal of Developmental Biology – Springer Journals
Published: Jul 17, 2006
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