Russian Journal of Developmental Biology; Vol. 31, No. 4, 2000, pp. 233-269. From Ontogenez, Vol. 31, No. 4, 2000, pp. 284-320. Original English Text Copyright 9 2000. Abstracts of Papers and Posters at the International Symposium on the Inactivation of X Chromosomes in Mammals ~ Novosibirsk, September 6-12, 1999 PAPERS The Effects of Xist Transgenes on the Mouse Y Chromosome M. L. Ager*, S. Duthie**, S. Morse*, N. Brockdorff**, and S. D. M. Brown* * MRC Mammalian Genetics Unit and UK Mouse Genome Center, Harwell, UK ** X-Inactivation Group, MRC Clinical Sciences Center, London, UK Much of the transgenic work involving the Xist gene function in every cell, as we only see approximately has been carried out in ES cells. We have constructed a 50% of cells with stable Xist expression. After inactiva- mouse line containing four copies of a 240 kb XistYAC tion has occurred (8.5 dpc), we no longer see Xist expres- inserted near the distal end of the mouse Y chromo- sion from the X chromosome and see stable Xist expres- some. Here, we demonstrate that the Xist transgenes sion from the Y chromosome in about 20% of cells. can function as a counting center in
Russian Journal of Developmental Biology – Springer Journals
Published: Nov 18, 2007
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera