A triple color FISH technique for mouse chromosome identification

A triple color FISH technique for mouse chromosome identification Short Communications Incorporating Mouse Genome Mammalian Genome 12, 462–465 (2001). © Springer-Verlag New York Inc. 2001 DOI: 10.1007/s003350020038 1 3 2 2 1 3 Octavian Henegariu, Judit Dunai, Xiao-Ning Chen, Julie R. Korenberg, David C. Ward, John M. Greally Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA Departments of Pediatrics and Human Genetics, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA Department of Medicine (Hematology), Ullman 925, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA Received: 23 December 2000 / Accepted: 8 February 2001 New applications for mouse molecular cytogenetics are emerging, specialists, as many as six fluorescent dyes are required for human including the definition of transgene integration sites in epigenet- and mouse chromosome identification in standard multiplex FISH ics studies (Alami et al. 2000), the characterization of the mouse (M-FISH) techniques (Speicher et al. 1996). This requires micros- genome following increasingly sophisticated techniques for its en- copy and imaging facilities found only in specialized centers. gineering (Su et al. 2000) and the screening for cytogenetic ab- We have previously described a set of BACs that map close to normalities in cell lines, such http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

A triple color FISH technique for mouse chromosome identification

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Copyright © 2001 by Springer-Verlag New York Inc.
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
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