A second locus encoding elevated phosphoglycerate mutase activity (Pgam2e) maps to mouse Chromosome 4

A second locus encoding elevated phosphoglycerate mutase activity (Pgam2e) maps to mouse... 296 Mammalian Genome 8, Brief Data Reports Jackson BSS D4Mitl2 '.Brcal, Grn, Pea3 6.1 .D11Hun18 -D11Bit14, D11MitlO D4Mit203 3.1 cMI -D11Bit15 D4Mit204 4.1 -D11Hun20 -D 11Hun21 D4Mit134 1.0 Pgam2e 1.0 D4Mit54 .Fasn, Hfh4, Pad3, D11Xrf16, D11Xrfl07 4.1 Fig. 1. Localization of Pad3 on the distal end of mouse Chr 11 with The D4Mit158 D4Mitl70 Jackson Laboratory BSS panel [7]. The map is depicted with the centro- 3.1 mere toward the top. A 3-cM scale bar is shown to the left of the figure. It appears that Pad3 is among the cluster of markers that is the most distal on D4Mit189 the Jackson BSS Chr 11 map. Fig. 1. A partial map of mouse Chr 4 with the distances in cM between each pair of loci. sarcomas [10], and a chimeric fusion protein involving the AFXI gene has been implicated in an acute lymphocytic leukemia [11]. In addition, the avian retroviral oncogene qin is a member of the Pgam2elNeu-(1.O + l.O)-D4Mit54-(4.1 + 2.0)-D4Mit158- forkhead gene family [11]. The possibility that the Hfh4 gene may D4Mit170-(3.1 + 1.7)-D4Mit189 (distances in cM) (Fig. 1). be affected by MMTV integration at the Pad3 locus is being tested. Method of mapping: Pgam2e 1Ne" was http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

A second locus encoding elevated phosphoglycerate mutase activity (Pgam2e) maps to mouse Chromosome 4

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Copyright © 1997 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
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