Childs Nerv Syst (2017) 33:1427 DOI 10.1007/s00381-017-3533-8 AUTHOR'S REPLY A reply to the letter to the editor by Nima Derakhshan and Mahsa Roshanfarzad with regard to the paper BPandora’sbox: eosinophilic granuloma at the cerebellopontine angle—should we open it?^ 1 2 Ahmet Öğrenci & Murat Şakir Ekşi Received: 2 July 2017 /Accepted: 6 July 2017 /Published online: 17 July 2017 Springer-Verlag GmbH Germany 2017 We thank to Drs. Derakhshan and Roshanfarzad for their in- they insisted on this fact in their letter. They did not give terest in our paper BPandora’s box: eosinophilic granuloma at details about clinical presentation and laboratory work-up of the cerebellopontine angle—should we open it?^ . They their patient. So, it is hard to make a further comment on their have stated their concerns about our paper in their letter to case at this point. the editor. We gave our answers and made our comments We, once again, insist on conducting a multi-center collab- based upon their questions. oration and set up an international database to collect such Eosinophilic granuloma (EG) is a focal disease form of cases to perform a large-scaled clinical study and get more Langerhans cell histiocytosis (LCH) presenting in the skull, steps further ahead in clinical and therapeutic approach to femur, vertebrae, pelvis, mandible, and ribs; yet, multiple sites those patients with central nervous system EGs. of occurrence have been described in the literature with con- Compliance with ethical standards firmation of the pathology [2–5]. The second query of the authors was about approach to a Conflict of interest All the authors declare that there is no conflict of patient with intracranial EG. In our previous paper, we stated interest. that steroid therapy could be initiated if EG diagnosis was made via clinical, radiological, and laboratory findings with close monitoring of the patient. We agree that surgical option References is in the first line in case of life-threatening scenarios. However, we think it is too early to make a guideline for 1. Ogrenci A, Batcik OE, Eksi MS, Koban O (2016) Pandora’sbox: follow-up of patients with intracranial EGs in the absence of eosinophilic granuloma at the cerebellopontine angle—should we a large-scaled clinical study or a meta-analysis of the current open it? Childs Nerv Syst 32:1513–1516 2. Yokota S, Tada S, Sugimoto K, Kajimoto K, Kitamura T, Takahashi literature. K, Kimura I, Kozuka A, Namba J (1994) A case of pulmonary In their case of EG, the authors did not mention if they had eosinophilic granuloma with extrapulmonary involvement treated made a histopathological confirmation of the diagnosis; yet effectively with steroid hormone. Nihon Kyobu Shikkan Gakkai Zasshi 32:78–83 3. Mut M, Cataltepe O, Bakar B, Cila A, Akalan N (2004) Eosinophilic granuloma of the skull associated with epidural haematoma: a case * Murat Şakir Ekşi report and review of the literature. Childs Nerv Syst 20:765–769 email@example.com 4. Grant GA, Kim DK, Shaw CM, Berger MS (1999) Solitary eosino- philic granuloma of the temporal lobe: case report and review of the literature. Brain Tumor Pathol 16:55–59 Department of Neurosurgery, Ersoy Hospital, Istanbul, Turkey 5. Fukazawa T, Yanagihara T, Hamada K, Hamada T (1994) Department of Neurosurgery, Antalya Atatürk State Hospital, Multifocal eosinophilic granuloma presenting as progressive Gençlik Mah. Fevzi Çakmak Cad. 3. Mahmut Çil Apart. No: 77/7, brainstem and cerebellar dysfunction. J Neurol Neurosurg Muratpaşa, Antalya, Turkey Psychiatry 57:980–982
Child's Nervous System – Springer Journals
Published: Jul 17, 2017
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