Support Care Cancer (2018) 26:1345–1352 https://doi.org/10.1007/s00520-017-3961-8 ORIGINAL ARTICLE A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients 1 2 3 4 5 6 Gudrun Piringer & Michael Fridrik & Alfred Fridrik & Andreas Leiherer & August Zabernigg & Richard Greil & 7 8 9 10 1 11 Wolfgang Eisterer & Jörg Tschmelitsch & Alois Lang & Sophie Frantal & Sonja Burgstaller & Michael Gnant & Josef Thaler & on behalf of the Austrian Breast and Colorectal Cancer Study Group (ABCSG) Received: 19 March 2017 /Accepted: 6 November 2017 /Published online: 22 November 2017 Springer-Verlag GmbH Germany, part of Springer Nature 2017 Abstract analysis showed early study termination due to non- Introduction Despite advances in adjuvant chemotherapy, compliance in 10/30 patients (33.3%), disease progression in 20–30% of patients in stages II–III colorectal cancer will 4 patients (13.3%), and serious adverse events in 2 patients eventually relapse. Observational studies showed a reduction (6.7%). About half of patients (46.7%) completed the pilot in relapse rate, colon cancer-specific mortality, and overall study as planned. Biomarker analysis from 20 patients showed mortality by physical activity. Results from prospective ran-
Supportive Care in Cancer – Springer Journals
Published: Nov 22, 2017
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