A potential cellular host factor homologous to ZNF-136 can interact with truncated nonstructural protein 2 of hepatitis C virus

A potential cellular host factor homologous to ZNF-136 can interact with truncated nonstructural... The cytoplasmic portion of the NS2 protein of hepatitis C virus (HCV) fused with a thioredoxin (TrX)-His tag was expressed in BL21 (DE3) cells and purified using an Ni-NTA His resin. Using a pull-down assay, a specific protein from the cell lysate of HepG2 cell lines was isolated together with immobilized truncated NS2 protein using Ni-NTA resin. Through peptide mass fingerprinting, this specific protein was found to be homologous to a repressor of transcription, ZNF136. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

A potential cellular host factor homologous to ZNF-136 can interact with truncated nonstructural protein 2 of hepatitis C virus

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Publisher
Springer Vienna
Copyright
Copyright © 2014 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-013-1888-z
Publisher site
See Article on Publisher Site

References

  • Complex formation between hepatitis C virus NS2 and NS3 proteins
    Kiiver, K; Merits, A; Ustav, M

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