A novel gammaherpesvirus isolated from a black-tailed prairie dog ( Cynomys ludovicianus )

A novel gammaherpesvirus isolated from a black-tailed prairie dog ( Cynomys ludovicianus ) A new gammaherpesvirus, tentatively named cynomys herpesvirus 1 (CynGHV-1), was isolated from a black-tailed prairie dog ( Cynomys ludovicianus ). CynGHV-1 replicated cytopathogenically to moderate titers in various cell lines. Ten kb of the CynGHV-1 genome was sequenced using degenerate PCR and genomic cloning. Sequence similarities were found to different genes from known gammaherpesviruses. Phylogenetic analysis suggested that CynGHV-1 was in fact a novel virus closely related to representatives of different genera and unclassified members of the subfamily Gammaherpesvirinae . However, CynGHV-1 could not be assigned to any particular genus and therefore remains unclassified. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

A novel gammaherpesvirus isolated from a black-tailed prairie dog ( Cynomys ludovicianus )

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Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer-Verlag
Subject
Biomedicine; Virology; Infectious Diseases; Medical Microbiology
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-011-1024-x
Publisher site
See Article on Publisher Site

Abstract

A new gammaherpesvirus, tentatively named cynomys herpesvirus 1 (CynGHV-1), was isolated from a black-tailed prairie dog ( Cynomys ludovicianus ). CynGHV-1 replicated cytopathogenically to moderate titers in various cell lines. Ten kb of the CynGHV-1 genome was sequenced using degenerate PCR and genomic cloning. Sequence similarities were found to different genes from known gammaherpesviruses. Phylogenetic analysis suggested that CynGHV-1 was in fact a novel virus closely related to representatives of different genera and unclassified members of the subfamily Gammaherpesvirinae . However, CynGHV-1 could not be assigned to any particular genus and therefore remains unclassified.

Journal

Archives of VirologySpringer Journals

Published: Oct 1, 2011

References

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