A novel ENU-induced mutation, peewee, causes dwarfism in the mouse

A novel ENU-induced mutation, peewee, causes dwarfism in the mouse Mamm Genome (2009) 20:455 DOI 10.1007/s00335-009-9202-9 ERRATUM A novel ENU-induced mutation, peewee, causes dwarfism in the mouse Bokryeon Lee Æ Kiyoshi Kano Æ Jay Young Æ Simon WM. John Æ Patsy M. Nishina Æ Jurgen K. Naggert Æ Kunihiko Naito Published online: 30 July 2009 Springer Science+Business Media, LLC 2009 Abstract We identified a novel fertile autosomal reces- two introns, and an untranslated region of Slc10a4 did not sive mutation called peewee that results in dwarfing, in a find any sequence difference between the peewee mouse region-specific ENU-induced mutagenesis. These mice at and the C57BL/6 J mouse. Detailed analysis of peewee litter size were smaller those of other strains. Histological mice might provide novel molecular insights into the analysis revealed that the major organs appear normal, but complex mechanisms regulating body growth. abnormalities in cellular proliferation were observed in bone, liver, and testis. Haplotype analysis localized the peewee gene to a 3.3-Mb region between D5Mit83 and Erratum to: Mamm Genome DOI: 10.1007/s00335-009-9197-2 D5Mit356.3. There are 18 genes in this linkage area. We SM also performed in silico mapping using the PosMed In the above-mentioned article, published in this issue of program, which searches for connections among keywords Mammalian Genome, the corrected authors’ names are and genes in an interval, but no similar phenotype descriptions were found for these genes. In the peewee listed above. Citation of this article should read Lee et al. (2009) and mutant compared to the normal C57BL/6 J mouse, only Slc10a4 expression was lower. Our preliminary mutation not Bokryeon et al. (2009). analysis examining the nucleotide sequence of three exons, The online version of the original article can be found under doi: 10.1007/s00335-009-9197-2. B. Lee  K. Kano (&)  K. Naito Laboratory of Applied Genetics, Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo 113-8657, Japan e-mail: akano@mail.ecc.u-tokyo.ac.jp J. Young  S. WM. John  P. M. Nishina  J. K. Naggert The Jackson Laboratory, Bar Harbor, ME 04609, USA http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

A novel ENU-induced mutation, peewee, causes dwarfism in the mouse

Free
1 page

Loading next page...
1 Page
 
/lp/springer_journal/a-novel-enu-induced-mutation-peewee-causes-dwarfism-in-the-mouse-Az80UABg0N
Publisher
Springer-Verlag
Copyright
Copyright © 2009 by Springer Science+Business Media, LLC
Subject
Life Sciences; Zoology ; Anatomy ; Cell Biology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s00335-009-9202-9
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial