A new spontaneous deletion on Chromosome 17 including brachyury

A new spontaneous deletion on Chromosome 17 including brachyury Short Communications 9 Springer-Verlag New York Inc. 1997 Mammalian Genome 8, 932-933 (1997). Petra Bilinski, John Schimenti, Achim Gossler The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA Received: ll April 1997 / Accepted: 18 August 1997 A number of spontaneous or radiation-induced deletions in the the phenotype, suggesting that homozygous Del(17)T 7J embryos proximal regions of mouse Chromosome (Chr) 17 including the die. Considering the similar phenotypes and genetics of Del(17)T 7s brachyury (T) gene have been identified on the basis of the con- and brachyury, we tested whether Del(17)T 7J is a new allele of spicuous tail phenotypes caused by loss-of-T function (for ex- brachyury. We intercrossed mice carrying T and tufted (T 07++) ample, Selby 1973; Johnson 1974; Babiarz 1983; Beddington et al. (Lyon 1956) with heterozygous Del(17)T 7J mice and analyzed 1992; Herrmann and Kispert 1994). Recently, additional nested embryos at d 9.5 of embryonic development for the presence of the deletions were specifically induced in this region of the genome by brachyury phenotype. Out of 39 embryos analyzed, 10 (26%) irradiation of ES cells (You et al. 1997). Such deletions have showed a phenotype that was indistinguishable from the phenotype proven valuable http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

A new spontaneous deletion on Chromosome 17 including brachyury

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Publisher
Springer-Verlag
Copyright
Copyright © 1997 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900614
Publisher site
See Article on Publisher Site

Abstract

Short Communications 9 Springer-Verlag New York Inc. 1997 Mammalian Genome 8, 932-933 (1997). Petra Bilinski, John Schimenti, Achim Gossler The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA Received: ll April 1997 / Accepted: 18 August 1997 A number of spontaneous or radiation-induced deletions in the the phenotype, suggesting that homozygous Del(17)T 7J embryos proximal regions of mouse Chromosome (Chr) 17 including the die. Considering the similar phenotypes and genetics of Del(17)T 7s brachyury (T) gene have been identified on the basis of the con- and brachyury, we tested whether Del(17)T 7J is a new allele of spicuous tail phenotypes caused by loss-of-T function (for ex- brachyury. We intercrossed mice carrying T and tufted (T 07++) ample, Selby 1973; Johnson 1974; Babiarz 1983; Beddington et al. (Lyon 1956) with heterozygous Del(17)T 7J mice and analyzed 1992; Herrmann and Kispert 1994). Recently, additional nested embryos at d 9.5 of embryonic development for the presence of the deletions were specifically induced in this region of the genome by brachyury phenotype. Out of 39 embryos analyzed, 10 (26%) irradiation of ES cells (You et al. 1997). Such deletions have showed a phenotype that was indistinguishable from the phenotype proven valuable

Journal

Mammalian GenomeSpringer Journals

Published: Mar 21, 2009

References

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