A new perspective for nuclear medicine: expanding the indications for PSMA targeted imaging and therapy

A new perspective for nuclear medicine: expanding the indications for PSMA targeted imaging and... Eur J Nucl Med Mol Imaging (2017) 44:1611–1613 DOI 10.1007/s00259-017-3767-4 EDITORIAL COMMENTARY A new perspective for nuclear medicine: expanding the indications for PSMA targeted imaging and therapy 1 1 Frederik A. Verburg & Markus Luster Received: 20 June 2017 /Accepted: 21 June 2017 /Published online: 4 July 2017 Springer-Verlag GmbH Germany 2017 The erroneously named prostate specific membrane antigen Furthermore, even well before the introduction of PSMA (PSMA), also known by the functional description of targeted imaging and therapy it was already shown in immu- glutamatedecarboxypeptidase 2,has inrecentyears seena mas- nohistochemical studies that PSMA is also expressed in a sive upsurge in interest in nuclear medicine due to the newly variety of solid malignancies including e.g. breast cancer and gliomas [22]. Incidental findings on PSMA PET/CT per- available specific functional substrate tracers for both positron emission tomography (PET) imaging and radionuclide therapy formed for prostate cancer have already expanded this list of [1–12]. Because of its superior characteristics [13–15]PSMA PSMA expressing tumours by e.g. renal cell carcinoma and targetedimagingandtherapyhasbecomepartofroutineclinical thyroid cancer [23–31]. care in an almost unprecedented rapid adoption process and has However, in most non-prostate neoplasms PSMA is not replaced the previous clinical standard wherever the necessary expressed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Nuclear Medicine and Molecular Imaging Springer Journals

A new perspective for nuclear medicine: expanding the indications for PSMA targeted imaging and therapy

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology
ISSN
1619-7070
eISSN
1619-7089
D.O.I.
10.1007/s00259-017-3767-4
Publisher site
See Article on Publisher Site

Abstract

Eur J Nucl Med Mol Imaging (2017) 44:1611–1613 DOI 10.1007/s00259-017-3767-4 EDITORIAL COMMENTARY A new perspective for nuclear medicine: expanding the indications for PSMA targeted imaging and therapy 1 1 Frederik A. Verburg & Markus Luster Received: 20 June 2017 /Accepted: 21 June 2017 /Published online: 4 July 2017 Springer-Verlag GmbH Germany 2017 The erroneously named prostate specific membrane antigen Furthermore, even well before the introduction of PSMA (PSMA), also known by the functional description of targeted imaging and therapy it was already shown in immu- glutamatedecarboxypeptidase 2,has inrecentyears seena mas- nohistochemical studies that PSMA is also expressed in a sive upsurge in interest in nuclear medicine due to the newly variety of solid malignancies including e.g. breast cancer and gliomas [22]. Incidental findings on PSMA PET/CT per- available specific functional substrate tracers for both positron emission tomography (PET) imaging and radionuclide therapy formed for prostate cancer have already expanded this list of [1–12]. Because of its superior characteristics [13–15]PSMA PSMA expressing tumours by e.g. renal cell carcinoma and targetedimagingandtherapyhasbecomepartofroutineclinical thyroid cancer [23–31]. care in an almost unprecedented rapid adoption process and has However, in most non-prostate neoplasms PSMA is not replaced the previous clinical standard wherever the necessary expressed

Journal

European Journal of Nuclear Medicine and Molecular ImagingSpringer Journals

Published: Jul 4, 2017

References

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