Access the full text.
Sign up today, get DeepDyve free for 14 days.
C. Taylor, Rosenhan Ak, J. Raines, J. Rodriguez (2012)
An Arson Investigation by using Comprehensive Two-dimensional Gas Chromatography- Quadrupole Mass SpectrometryJournal of Forensic Research, 3
B. Sgorbini, C. Bicchi, C. Cagliero, C. Cordero, E. Liberto, P. Rubiolo (2015)
Herbs and spices: characterization and quantitation of biologically-active markers for routine quality control by multiple headspace solid-phase microextraction combined with separative or non-separative analysis.Journal of chromatography. A, 1376
C Brasseur, J Dekeirsschieter, EMJ Schotsmans (2012)
Comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the forensic study of cadaveric volatile organic compounds released in soil by buried decaying pig carcassesJ Chromatogr A, 1255
Wennan Zhao, Gangfeng Ouyang, J. Pawliszyn (2007)
Preparation and application of in-fibre internal standardization solid-phase microextraction.The Analyst, 132 3
Yoel Donchin, Avraham Rivkind, Jacob Bar-Ziv, Jehuda Hiss, Joseph Almog, Michael Drescher (1994)
Utility of postmortem computed tomography in trauma victims.The Journal of trauma, 37 4
S. Song, P. Marriott, P. Wynne (2004)
Comprehensive two-dimensional gas chromatography--quadrupole mass spectrometric analysis of drugs.Journal of chromatography. A, 1058 1-2
S. Reichenbach, Xue Tian, Qingping Tao, E. Ledford, Zhanpin Wu, O. Fiehn (2011)
Informatics for cross-sample analysis with comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry (GCxGC-HRMS).Talanta, 83 4
B. Mitrevski, Biljana Veleska, E. Engel, P. Wynne, S. Song, P. Marriott (2011)
Chemical signature of ecstasy volatiles by comprehensive two-dimensional gas chromatography.Forensic science international, 209 1-3
Pierre‐Hugues Stefanuto, Katelynn Perrault, S. Grabherr, V. Varlet, J. Focant (2016)
Postmortem Internal Gas Reservoir Monitoring Using GC×GC-HRTOF-MSSeparations, 3
J. Dekeirsschieter, Pierre‐Hugues Stefanuto, Catherine Brasseur, E. Haubruge, J. Focant (2012)
Enhanced Characterization of the Smell of Death by Comprehensive Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GCxGC-TOFMS)PLoS ONE, 7
D. Wichmann, F. Obbelode, H. Vogel, W. Hoepker, A. Nierhaus, S. Braune, G. Sauter, K. Pueschel, S. Kluge (2012)
Virtual Autopsy as an Alternative to Traditional Medical Autopsy in the Intensive Care UnitAnnals of Internal Medicine, 156
Katelynn Perrault, Katie Nizio, S. Forbes (2015)
A Comparison of One-Dimensional and Comprehensive Two-Dimensional Gas Chromatography for Decomposition Odour Profiling Using Inter-Year Replicate Field TrialsChromatographia, 78
Yanxiang Wang, J. O'Reilly, Yong Chen, J. Pawliszyn (2005)
Equilibrium in-fibre standardisation technique for solid-phase microextraction.Journal of chromatography. A, 1072 1
A. Kueh, P. Marriott, P. Wynne, J. Vine (2003)
Application of comprehensive two-dimensional gas chromatography to drugs analysis in doping control.Journal of chromatography. A, 1000 1-2
Katelynn Perrault, Pierre‐Hugues Stefanuto, L. Dubois, Dries Cnuts, Veerle Rots, J. Focant (2016)
A New Approach for the Characterization of Organic Residues from Stone Tools Using GC×GC-TOFMSSeparations, 3
B. Blokker, I. Wagensveld, A. Weustink, J. Oosterhuis, M. Hunink (2015)
Non-invasive or minimally invasive autopsy compared to conventional autopsy of suspected natural deaths in adults: a systematic reviewEuropean Radiology, 26
Pierre‐Hugues Stefanuto, Katelynn Perrault, Rebecca Lloyd, B. Stuart, Tapan Rai, S. Forbes, J.-F. Focant (2015)
Exploring new dimensions in cadaveric decomposition odour analysisAnalytical Methods, 7
J. Hinshaw (2004)
Comprehensive two-dimensional gas chromatographyLc Gc North America, 22
Katie Nizio, Katelynn Perrault, A. Troobnikoff, M. Ueland, S. Shoma, J. Iredell, P. Middleton, P. Middleton, Shari Forbes (2016)
In vitro volatile organic compound profiling using GC×GC-TOFMS to differentiate bacteria associated with lung infections: a proof-of-concept studyJournal of Breath Research, 10
S. Stadler, Pierre‐Hugues Stefanuto, Michał Brokl, S. Forbes, J. Focant (2013)
Characterization of volatile organic compounds from human analogue decomposition using thermal desorption coupled to comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.Analytical chemistry, 85 2
(2016)
Achieving a neartheoretical maximum in peak capacity gain for the forensic analysis of ignitable liquids using GC × GC-TOFMS. Separations 3:1–17
V. Varlet, C. Bruguier, S. Grabherr, M. Augsburger, P. Mangin, T. Uldin (2014)
Gas analysis of exhumed cadavers buried for 30 years: a case report about long time alterationInternational Journal of Legal Medicine, 128
M. Sebaiy, Abdullah El-Shanawany, M. Baraka, L. Abdel-Aziz, T. Isbell, C. Colyer (2016)
Determination of Morphine and Its Metabolites in Human Urine by Capillary Electrophoresis with Laser Induced Fluorescence Detection Employing On-Column Labeling with a New Boronic Acid Functionalized Squarylium Cyanine DyeSeparations, 3
G. Frysinger, Richard Gaines, C. Reddy (2002)
GC × GC--A New Analytical Tool For Environmental ForensicsEnvironmental Forensics, 3
V. Varlet, F. Smith, N. Giuliani, Caroline Egger, A. Rinaldi, Alejandro Dominguez, C. Chevallier, C. Chevallier, C. Bruguier, C. Bruguier, M. Augsburger, Patrice Mangin, S. Grabherr (2015)
When gas analysis assists with postmortem imaging to diagnose causes of death.Forensic science international, 251
Heather Bean, C. Rees, Jane Hill (2016)
Comparative analysis of the volatile metabolomes of Pseudomonas aeruginosa clinical isolatesJournal of Breath Research, 10
Pierre‐Hugues Stefanuto, Katelynn Perrault, J. Focant, S. Forbes (2015)
Fast Chromatographic Method for Explosive ProfilingChromatography, 2
V. Varlet, F. Smith, S. Froidmont, A. Domínguez, A. Rinaldi, M. Augsburger, P. Mangin, S. Grabherr (2013)
Innovative method for carbon dioxide determination in human postmortem cardiac gas samples using headspace-gas chromatography-mass spectrometry and stable labeled isotope as internal standard.Analytica chimica acta, 784
LaTara Rust, Katie Nizio, S. Forbes (2016)
The influence of ageing and surface type on the odour profile of blood-detection dog training aidsAnalytical and Bioanalytical Chemistry, 408
Katie Nizio, J. Cochran, S. Forbes (2016)
Achieving a Near-Theoretical Maximum in Peak Capacity Gain for the Forensic Analysis of Ignitable Liquids Using GC×GC-TOFMSSeparations, 3
(2016)
Troobnikoff AN et al (2016) In vitro volatile organic compound profiling using GC×GC-TOFMS to differentiate bacteria associated with lung infections: a proof-of-concept study
A. Silva, A. Silva, H. Pereira, Alessandro Casilli, F. Conceição, F. Neto (2009)
Analytical challenges in doping control: Comprehensive two-dimensional gas chromatography with time of flight mass spectrometry, a promising option.Journal of chromatography. A, 1216 14
S. Paczkowski, S. Schütz (2011)
Post-mortem volatiles of vertebrate tissueApplied Microbiology and Biotechnology, 91
(2001)
2016) A new approach for the characterization of organic residues from stone tools using GC×GC-TOFMS. Separa t ions 3:1–16
In forensic casework, non-invasive and minimally-invasive methods for postmortem examinations are extremely valuable. Whole body postmortem computed tomography (PMCT) is often used to provide visualization of the internal characteristics of a body prior to more invasive procedures and has also been used to locate gas reservoirs inside the body to assist in determining cause of death. Preliminary studies have demonstrated that exploiting the volatile organic compounds (VOCs) located in these gas reservoirs by comprehensive two-dimensional gas chromatography–high-resolution time-of-flight mass spectrometry (GC×GC-HRTOF-MS) may assist in providing information regarding the postmortem interval. The aim of the current study was to further develop the procedures related to solid-phase microextraction (SPME) and GC×GC-HRTOF-MS analysis of gas reservoirs collected from deceased individuals. SPME fiber extraction parameters, internal standard approach, and sample stability were investigated. Altering the SPME parameters increased the selectivity and sensitivity for the VOC profile, and the use of a mixed deuterated internal standard contributed to data quality. Samples were found to be stable up to 6 weeks but were recommended to be analyzed within 4 weeks due to higher variation observed beyond this point. In addition, 29 VOC markers of interest were identified, and heart and/or abdominal cavity samples were suggested as a possible standardized sampling location for future studies. The data presented in this study will contribute to the long-term goal of producing a routine, accredited method for minimally-invasive VOC analysis in postmortem examinations.
International Journal of Legal Medicine – Springer Journals
Published: Jun 15, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.