Mammalian Genome 11, 464–465 (2000). Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 A locus responsible for osteochondrodysplasia (ocd) is located on rat Chromosome 11 Hiroetsu Suzuki, Sachiyo Fukaya, Kenichi Saito, Katsushi Suzuki Department of Veterinary Physiology, Nippon Veterinary and Animal Science University, 1-7-1 Kyonano-cho, Musashino-shi, Tokyo 180-8602, Japan Received: 30 November 1999 / Accepted: 18 February 2000 Rats of the congenital osteochondrodysplasia (OCD) strain display lethal dwarfing characteristics that are controlled by an autosomal single recessive allele (ocd). External features of these ocd/ocd rats include systemic subcutaneous edema, protruded tongue, cleft plate, and shortening of the extremities, head, body, and tail (Su- zuki et al. 1987, 1988). These ocd/ocd rats also exhibit renal anomalies (Kikukawa et al. 1989a) and die shortly after birth from respiratory insufficiency, resulting from both morphological and functional abnormalities of the respiratory system (Kikukawa et al. 1989b, 1989c). Irregular columnization, expansion of chondro- cytes, widespread areas of necrosis, and weak stainability of gly- cosaminoglycans (GAGs) are observed in the epiphyseal cartilage of ocd/ocd neonates (Kikukawa et al. 1991a). Electron micro- scopic examination of the cartilage reveals a decrease in the size of GAG granules and the presence of large collagen bundles in the
Mammalian Genome – Springer Journals
Published: Feb 5, 2014
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera