Psychopharmacology (2018) 235:695–708 https://doi.org/10.1007/s00213-017-4785-4 ORIGINAL INVESTIGATION A high working memory load prior to memory retrieval reduces craving in non-treatment seeking problem drinkers 1,2 2,3,4 5 5 Anne Marije Kaag & Anna E. Goudriaan & Taco J. De Vries & Tommy Pattij & 1,2 Reinout W. Wiers Received: 21 June 2017 /Accepted: 7 November 2017 /Published online: 27 November 2017 The Author(s) 2017. This article is an open access publication Abstract memory load prior to memory retrieval (the original control Background Reconsolidation-based interventions have been condition) strongly reduced retrieval-induced craving and suggested to be a promising treatment strategy for substance craving for alcohol at follow-up. use disorders. In this study, we aimed to investigate the effec- Conclusion Whereas the neurocognitive mechanism behind tiveness of a working memory intervention to interfere with this effect needs to be further investigated, the current findings the reconsolidation of alcohol-related memories in a sample of suggest that, if replicated, working memory training prior to non-treatment seeking heavy drinkers. addiction-related memory retrieval has the potential to be- Methods Participants were randomized to one of the two con- come an effective (adjunctive) intervention in the treatment ditions that underwent a 3-day intervention: in the experimen- of substance
Psychopharmacology – Springer Journals
Published: Nov 27, 2017
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