Mammalian Genome 9, 390-391 (1998). Mammalian Genome Incorporating Mouse Genome © Springer-Verlag New York Inc. 1998 A high-resolution genetic map of mouse Chromosome 19 encompassing the muscle-deficient osteochondrodystrophy (mdf-ocd) region Christophe Poirier, * Stephan Blot,2 Marie Fernandes, 3 Georges F. Carle, 3 Viktor Stanescu, 4 Ritta Stanescu, 4 Jean-Louis Guenet l 'Unite de Genetique des Manuniferes, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France 2Unite Pedagogique de Medecine, Ecole Nationale Veterinaire d'Alfort, 94704 Maisons-Alfort, France 3Laboratorire d'Etude du Genome Murin, C.N.R.S. UMR 6549, Faculte de Medecine, 06107 Nice Cedex 2, France 4INSERM, U383, Hopital des Enfants Malades, 75743 Paris Cedex 15, France Received: 5 September 1992 / Accepted: 16 January 1998 Muscle deficient (mdf) is an autosomal recessive mutation of the our intraspecific cross, we also mapped in the vicinity of the mdf/ neuromuscular type which arose spontaneously in 1974, in a ocd loci the Rela gene, which encodes the p65 subunit of NFKB. C57BL/6 colony, at The Jackson Laboratory (Womack et al. This mapping was achieved by scoring the interstrain single strand 1980). Homozygotes for this mutation can first be detected at 5-6 conformation polymorphism (Orita et al. 1989) of a 245-bp in- weeks
Mammalian Genome – Springer Journals
Published: Mar 27, 2009
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