A four-component Pfitzinger reaction: synthesis of 2-pyronylquinolin-4-carbamides

A four-component Pfitzinger reaction: synthesis of 2-pyronylquinolin-4-carbamides OH H N O NH OAc O O EtOH OH CH C(OEt) 3 3 O O X= H, Cl, Br, NO ,OCH 2 3 Keywords Catalysis  Four-component reaction  Pfitzinger’s quinoline synthesis 4-Hydroxycoumarin  4-Hydroxy-2H-pyran-2-one & Kurosh Rad-Moghadam radmm@guilan.ac.ir Chemistry Department, Islamic Azad University, Tehran-North Branch, Tehran, Iran Chemistry Department, University of Guilan, Rasht, P.O. Box 41335-1914, Iran 123 4402 S. Y. Kalurazi et al. Introduction Multicomponent reactions (MCRs) typically correspond with molecular-diversity- oriented strategies that enable us to reach maximal structural complexities through minimal processes. These reactions, with a strategy that has already been taken by nature with the aid of enzymes, are becoming quite popular in the chemical community due to being designed by merge of several individual compatible reactions which operate in a sequential manner. A recurrent approach in this context is to make use of even simpler starting materials to yield one or more of the substrates in situ. This strategy usually decreases the cost of synthesis and provides a pool of diverse starting molecules for use in the generation of diversely functionalized products. On the other hand; however, multiplication of the reacting components may increase the chance of side reactions. Hence, efficient MCRs http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

A four-component Pfitzinger reaction: synthesis of 2-pyronylquinolin-4-carbamides

Loading next page...
 
/lp/springer_journal/a-four-component-pfitzinger-reaction-synthesis-of-2-pyronylquinolin-4-2Me3Ovlfna
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-017-2885-8
Publisher site
See Article on Publisher Site

Abstract

OH H N O NH OAc O O EtOH OH CH C(OEt) 3 3 O O X= H, Cl, Br, NO ,OCH 2 3 Keywords Catalysis  Four-component reaction  Pfitzinger’s quinoline synthesis 4-Hydroxycoumarin  4-Hydroxy-2H-pyran-2-one & Kurosh Rad-Moghadam radmm@guilan.ac.ir Chemistry Department, Islamic Azad University, Tehran-North Branch, Tehran, Iran Chemistry Department, University of Guilan, Rasht, P.O. Box 41335-1914, Iran 123 4402 S. Y. Kalurazi et al. Introduction Multicomponent reactions (MCRs) typically correspond with molecular-diversity- oriented strategies that enable us to reach maximal structural complexities through minimal processes. These reactions, with a strategy that has already been taken by nature with the aid of enzymes, are becoming quite popular in the chemical community due to being designed by merge of several individual compatible reactions which operate in a sequential manner. A recurrent approach in this context is to make use of even simpler starting materials to yield one or more of the substrates in situ. This strategy usually decreases the cost of synthesis and provides a pool of diverse starting molecules for use in the generation of diversely functionalized products. On the other hand; however, multiplication of the reacting components may increase the chance of side reactions. Hence, efficient MCRs

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Feb 13, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off