Intensive Care Med (2017) 43:1436–1437 DOI 10.1007/s00134-017-4823-z CORRESPONDENCE A fixed correction of absolute transpulmonary pressure may not be ideal for clinical use Discussion on “Accuracy of esophageal pressure to assess transpulmonary pressure during mechanical ventilation” 1* 2 2 3 4 Elias Baedorf Kassis , Stephen H. Loring , Daniel Talmor , Pierpaolo Terragni , Luciana Mascia and V. Marco Ranieri © 2017 Springer-Verlag Berlin Heidelberg and ESICM avoided choosing a specific correction value, recognizing Initial correspondence from Dr. Baedorf Kassis inter-individual variation and uncertainty in this relation- et al. ship . While we admire the elegance of Terragni’s study Dear Editor, and are excited to see further work, the use of P in esti- We read with interest the letter by Terragni  describing es mating transpulmonary pressure and parenchymal stress a marvelous experiment before and after lung transplan- must be understood in the context of these uncertainties, tation which suggested that pleural pressure is 5 cmH O and we are cautious about over-interpretation and clini- lower than esophageal pressure (P ). We have made es cal application. similar estimates based on the 3–7 cmH O increase in P moving from upright to supine, but there is consider- es Reply from Dr. Terragni et al.
Intensive Care Medicine – Springer Journals
Published: May 15, 2017
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