Eur Child Adolesc Psychiatry (2018) 27:377–384 https://doi.org/10.1007/s00787-017-1058-z ORIGINAL CONTRIBUTION A double‑blind placebo‑controlled randomised trial of omega‑3 supplementation in children with moderate ADHD symptoms 1,2,3,12 4,5,6 1 1 Catherine Cornu · Catherine Mercier · Tiphanie Ginhoux · Sandrine Masson · 4 2,3 1,2,3 1 7 8 Julie Mouchet · Patrice Nony · Behrouz Kassai · Valérie Laudy · Patrick Berquin · Nathalie Franc · 9 10 11 Marie‑France Le Heuzey · Hugues Desombre · Olivier Revol Received: 14 February 2017 / Accepted: 23 September 2017 / Published online: 5 October 2017 © Springer-Verlag GmbH Germany 2017 Abstract age was 9.90 (SD 2.62) years and 78.4% were boys. The Objective Clinical trials and inconclusive meta-analyses inclusion ADHD-RS-IV at was 37.31 (SD 8.40). The total have investigated the effects of omega-3 supplements in ADHD-RS-IV score reduction was greater in the placebo children with Attention-Deficit Hyperactivity Disorder group than in the DHA–EPA group: −19 (−26, −12) % and (ADHD). We performed a randomised placebo-controlled −9.7 (−16.6, −2.9) %, respectively, p = 0.039. The other trial to evaluate the efficacy of omega-3 fatty acids. components of the Conners score had a similar variation but Methods Children aged 6–15 years with established the differences between groups were not significant. Two diagnosis of ADHD were randomised 1:1 to receive either patients in the DHA–EPA
European Child & Adolescent Psychiatry – Springer Journals
Published: Oct 5, 2017
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