A copper(II) complex of a semicarbazone: crystal structure, spectroscopic analysis and cytotoxicity against human cancer cell lines

A copper(II) complex of a semicarbazone: crystal structure, spectroscopic analysis and... Transit Met Chem (2017) 42:503–508 DOI 10.1007/s11243-017-0154-8 A copper(II) complex of a semicarbazone: crystal structure, spectroscopic analysis and cytotoxicity against human cancer cell lines 1 1 1 1 • • • • Claudia C. Gatto Patrı´cia M. Miguel Carolane M. Almeida Pedro H. O. Santiago 2 2,3 Carlos R. K. Paier Claudia Pessoa Received: 20 March 2017 / Accepted: 24 May 2017 / Published online: 31 May 2017 Springer International Publishing Switzerland 2017 Abstract A Cu(II) complex of 2-hydroxyacetophenone biological activity, although there has so for been limited N(4)-phenyl semicarbazone (H L) has been prepared, and understanding of their molecular mechanisms of action [4]. its crystal structure is reported. The single-crystal X-ray Several transition metal ions play important roles in living study reveals a dimeric structure with a distorted square organisms, and copper is an essential trace metal for both planar coordination geometry around each copper atom, animals and plants. Several types of copper-based com- with an ONO-donor ligand and l -oxo group located plexes have been extensively investigated as potential between the two copper atoms. The secondary coordination antitumor agents [5]. It has been established that copper(II) sphere of Cu(II) is six-coordinate, with a NO ion and is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transition Metal Chemistry Springer Journals

A copper(II) complex of a semicarbazone: crystal structure, spectroscopic analysis and cytotoxicity against human cancer cell lines

Loading next page...
 
/lp/springer_journal/a-copper-ii-complex-of-a-semicarbazone-crystal-structure-spectroscopic-pBBkT0td8w
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing Switzerland
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry; Organometallic Chemistry
ISSN
0340-4285
eISSN
1572-901X
D.O.I.
10.1007/s11243-017-0154-8
Publisher site
See Article on Publisher Site

Abstract

Transit Met Chem (2017) 42:503–508 DOI 10.1007/s11243-017-0154-8 A copper(II) complex of a semicarbazone: crystal structure, spectroscopic analysis and cytotoxicity against human cancer cell lines 1 1 1 1 • • • • Claudia C. Gatto Patrı´cia M. Miguel Carolane M. Almeida Pedro H. O. Santiago 2 2,3 Carlos R. K. Paier Claudia Pessoa Received: 20 March 2017 / Accepted: 24 May 2017 / Published online: 31 May 2017 Springer International Publishing Switzerland 2017 Abstract A Cu(II) complex of 2-hydroxyacetophenone biological activity, although there has so for been limited N(4)-phenyl semicarbazone (H L) has been prepared, and understanding of their molecular mechanisms of action [4]. its crystal structure is reported. The single-crystal X-ray Several transition metal ions play important roles in living study reveals a dimeric structure with a distorted square organisms, and copper is an essential trace metal for both planar coordination geometry around each copper atom, animals and plants. Several types of copper-based com- with an ONO-donor ligand and l -oxo group located plexes have been extensively investigated as potential between the two copper atoms. The secondary coordination antitumor agents [5]. It has been established that copper(II) sphere of Cu(II) is six-coordinate, with a NO ion and is

Journal

Transition Metal ChemistrySpringer Journals

Published: May 31, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off