The aim of this study was to systematically investigate the apatite layer formation and protein adsorption on the bioceramics, trying to reveal their relationship and the mechanisms of the process. Four different materials, hydroxyapatite (HA), apatite/ wollastonite bioactive glass ceramics (BGC), biphasic calcium phosphate (BCP), and nano-hydroxyapatite (nHA), were prepared to meet the specific tissue engineering scaffold requirements. The porous samples in four groups were immersed into simulated body fluid (SBF) solution, and the structural and morphological changes for different times (maximum of 14 days) were analyzed. Then, the effect of their structure and chemical composition on protein adsorption capacity was systematically compared. . . . Keywords Porous bioceramic Bioactive glass ceramic Nanoceramic Scaffold Introduction there is a vital need to conduct comparative studies among these ceramics under well-controlled conditions [6–8]. Bioceramics, such as bioactive glass and calcium phosphates, In this study, we synthesized four types of scaffolds (nHA, HA, have been widely studied for orthopedic and dental applica- BCP, and BGC) aiming to reveal the relationship between apatite tions due to their excellent biocompatibility and bioactivity formation and protein adsorption ability among these bioceramics. [1–3]. The proteins from the surrounding body fluids can be As the porosity was
Journal of the Australian Ceramic Society – Springer Journals
Published: Jun 6, 2018
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