Keywords Yonemitsu condensation 3-Indole derivatives Catalyst-free Ultrasonic irradiation Aqueous glycerol Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2675-8) contains supplementary material, which is available to authorized users. & Cheng-Wei Lu ¨ firstname.lastname@example.org School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, People’s Republic of China 123 944 C.-W. Lu ¨ et al. Introduction The efﬁcient and high-throughput synthesis of complex organic molecules with a lower impact on the environment is one of the most important objectives in modern synthetic organic and green chemistry [1, 2]. As the pressure to produce the myriad of substances required by society in an environmentally benign fashion has continued to increase, it is now essential for chemists to develop new greener synthetic pathways under natural conditions as many as possible . Green chemistry utilizes a set of principles that optimize the synthetic methodologies to reduce pollution, cost, and tedious work-ups [4–6]. One of the key areas of green chemistry is the reduction or elimination of expensive catalysts in chemical processes and the replacement of hazardous solvents with environment-friendly solvents [7–9]. Glycerol is the only green solvent like water that can combine at a low price with
Research on Chemical Intermediates – Springer Journals
Published: Jul 28, 2016
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