A case of ureteral obstruction and sepsis induced by bladder perforation following intravesical bacillus Calmette–Guérin successfully treated with an antituberculous agent, antimicrobial chemotherapy and percutaneous urine drainage

A case of ureteral obstruction and sepsis induced by bladder perforation following intravesical... We report a case of ureteral obstruction and sepsis induced by bladder perforation following intravesical bacillus Calmette– Guérin (BCG) that was successfully treated non-surgically. A 56-year-old man was diagnosed with non-muscle invasive bladder cancer. He was treated with intravesical BCG instillation after transurethral resection of the bladder tumor. Just before the 6th course of intravesical BCG, the patient was diagnosed with bladder perforation and developed ureteral obstruction and sepsis associated with BCG. He was treated successfully with an antituberculous agent, antimicrobial chemotherapy and percutaneous urine drainage. Bladder perforation associated with BCG is a very rare adverse event that causes severe sepsis. Keywords Bladder perforation · Bacillus Calmette–Guérin · Sepsis AbbreviationsEB Ethambutol BCG Bacillus Calmette–GuérinAE Adverse event EAU The European Association of UrologyMMC Mitomycin C NCCN N ational Comprehensive Cancer Network TURBT T ransurethral resection of the bladder Introduction tumor UC Urothelial carcinoma Intravesical bacillus Calmette–Guérin (BCG) therapy is use- Cis Carcinoma in situ ful for adjuvant treatment of patients with high- and inter- CS Cystoscopy mediate-risk non-muscle-invasive bladder cancer (NMIBC) CT Computed tomography [1–3]. The European Association of Urology (EAU) and PNS Percutaneous nephrostomy National Comprehensive Cancer Network (NCCN) guide- PCR Polymerase chain reaction lines recommend that patients with high- and intermediate- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Cancer Conference Journal Springer Journals

A case of ureteral obstruction and sepsis induced by bladder perforation following intravesical bacillus Calmette–Guérin successfully treated with an antituberculous agent, antimicrobial chemotherapy and percutaneous urine drainage

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Publisher
Springer Japan
Copyright
Copyright © 2018 by The Japan Society of Clinical Oncology
Subject
Medicine & Public Health; Oncology; Surgical Oncology
eISSN
2192-3183
D.O.I.
10.1007/s13691-018-0331-4
Publisher site
See Article on Publisher Site

Abstract

We report a case of ureteral obstruction and sepsis induced by bladder perforation following intravesical bacillus Calmette– Guérin (BCG) that was successfully treated non-surgically. A 56-year-old man was diagnosed with non-muscle invasive bladder cancer. He was treated with intravesical BCG instillation after transurethral resection of the bladder tumor. Just before the 6th course of intravesical BCG, the patient was diagnosed with bladder perforation and developed ureteral obstruction and sepsis associated with BCG. He was treated successfully with an antituberculous agent, antimicrobial chemotherapy and percutaneous urine drainage. Bladder perforation associated with BCG is a very rare adverse event that causes severe sepsis. Keywords Bladder perforation · Bacillus Calmette–Guérin · Sepsis AbbreviationsEB Ethambutol BCG Bacillus Calmette–GuérinAE Adverse event EAU The European Association of UrologyMMC Mitomycin C NCCN N ational Comprehensive Cancer Network TURBT T ransurethral resection of the bladder Introduction tumor UC Urothelial carcinoma Intravesical bacillus Calmette–Guérin (BCG) therapy is use- Cis Carcinoma in situ ful for adjuvant treatment of patients with high- and inter- CS Cystoscopy mediate-risk non-muscle-invasive bladder cancer (NMIBC) CT Computed tomography [1–3]. The European Association of Urology (EAU) and PNS Percutaneous nephrostomy National Comprehensive Cancer Network (NCCN) guide- PCR Polymerase chain reaction lines recommend that patients with high- and intermediate-

Journal

International Cancer Conference JournalSpringer Journals

Published: May 31, 2018

References

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