Journal of Neuro-Oncology (2018) 137:215–218 https://doi.org/10.1007/s11060-017-2705-4 LE T TER TO THE EDITOR A case of unusually long survival after leptomeningeal carcinomatosis diagnosis 1,2 3 2 Marianna Riolo · Emilio Ciusani · Andrea Salmaggi Received: 4 October 2017 / Accepted: 24 November 2017 / Published online: 2 December 2017 © Springer Science+Business Media, LLC, part of Springer Nature 2017 To the Editor, performed, revealing the presence of diffuse leptomenin- geal contrast along optic chiasm, V, VII, VIII cranial nerves, Relating to the letter “Leptomeningeal carcinomatosis conus and cauda, with an initial increase in lateral ventricu- 9 years after nodule resection for pulmonary carcinoma lar size, indicating possible leptomeningeal metastasis. CSF in situ: MRS and pathological studies” reported in your Sep- analysis showed high protein concentration (355 mg/dl) tember 2017, Vol 34, Issue 2, we agree that leptomeningeal and lymphocytic pleocytosis (43/mm ), but cytology was metastases (LM) are difficult to diagnose, and, when this not positive for the presence of malignant cells. Because occurs, patient’s prognosis is poor with a median overall thoracic and abdomen CT scan were negative for metastatic survival of 3,3 months from the time of the diagnosis [1, disease, a total body PET was performed and it revealed 2]. Nevertheless, some reports
Journal of Neuro-Oncology – Springer Journals
Published: Dec 2, 2017
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