Eur J Nucl Med Mol Imaging (2017) 44:1695–1701 DOI 10.1007/s00259-017-3701-9 ORIGINAL ARTICLE Ga-DOTATATE PET/CT in recurrent medullary thyroid carcinoma: a lesion-by-lesion comparison with In-octreotide SPECT/CT and conventional imaging 1,2 1 1 Lilian Yuri Itaya Yamaga & Marcelo L. Cunha & Guilherme C. Campos Neto & 1 3 3 1 Marcio R. T. Garcia & Ji H. Yang & Cleber P. Camacho & Jairo Wagner & Marcelo B. G. Funari Received: 7 December 2016 /Accepted: 3 April 2017 /Published online: 20 April 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract p = 0.005) in comparison to SPECT/CT (16 lesions). There Purpose The aim of this study was to prospectively compare was no significant difference between PET/CT and CI for the the detection rate of Ga-DOTATATE PET-CT with total number of detected lesions (p = 0.734). PET/CT detected In-octreotide SPECT-CT and conventional imaging (CI) more lesions than SPECT/CT regardless of the organ. PET/CT in medullary thyroid carcinoma (MTC) patients with in- detected more bone lesions but missed some neck nodal metas- creased calcitonin (Ctn) levels but negative CI after tases evidenced by CI. The number of lesions per region dem- thyroidectomy. onstrated by PET/CT and CI were similar in the other sites. Methods
European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Apr 20, 2017
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