Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Pharmacokinetics of Psychotropic Drugs in the Elderly

Pharmacokinetics of Psychotropic Drugs in the Elderly CHAPTER 4 Pharmacokinetics of Psychotropic Drugs in the Elderly* LI SA L. VON MOLTK E & D AVID j. GREENBLAIT DEl'ARTM ENl OF PHARMA COLOGY AND EXI'EI~IM ENTAL TH ERAPEUTICS, TuFfS U NIVE RSITY ScHOOL OF MEDICINE, AND THE DIVISION OF CLiNIC t\L P HARMACOlOCY, NEW ENGLAND MEDI CA L CENTER rescr iption and nonprescription drug u se increases w ith age, and psyc hotropics rank high among the therapeutic classes that are Pmost utilized. The e lderly, usually defined as those over 6S years of age, are a highly heterogenous group, with la rge va riability in the ir overa ll health sta tus (Avo rn , 1998; Chrischilles et aI., 1992; Lebowitz, et aL, 1997; Lebowitz, Pea rson , & Cohen, 1998 ). In the aggrega te, th ey are more vulnerable to the hazards of pharmacothe rapy (Ca mpbell, 1991; Cumm in g, 1(98). Both pharmacokinetic and pharmacodynam ic d iffer­ e nces havc been descr ibed after psychotropic drugs are administered to ag in g ind iYiduals (&~rtz e t al.. 1997; Greenblatt, Harma tz, & Shader, 1991; 1991b; Nikai d o, Ellinwood , Heatherl y, & Gup ta , 1990; von Moltke, Greenb latt http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Gerontology & Geriatrics Springer Publishing

Pharmacokinetics of Psychotropic Drugs in the Elderly

Loading next page...
 
/lp/springer-publishing/pharmacokinetics-of-psychotropic-drugs-in-the-elderly-0lDMpGgAyq
Publisher
Springer Publishing
ISSN
0198-8794
eISSN
1944-4036
DOI
10.1891/0198-8794.19.1.53
Publisher site
See Article on Publisher Site

Abstract

CHAPTER 4 Pharmacokinetics of Psychotropic Drugs in the Elderly* LI SA L. VON MOLTK E & D AVID j. GREENBLAIT DEl'ARTM ENl OF PHARMA COLOGY AND EXI'EI~IM ENTAL TH ERAPEUTICS, TuFfS U NIVE RSITY ScHOOL OF MEDICINE, AND THE DIVISION OF CLiNIC t\L P HARMACOlOCY, NEW ENGLAND MEDI CA L CENTER rescr iption and nonprescription drug u se increases w ith age, and psyc hotropics rank high among the therapeutic classes that are Pmost utilized. The e lderly, usually defined as those over 6S years of age, are a highly heterogenous group, with la rge va riability in the ir overa ll health sta tus (Avo rn , 1998; Chrischilles et aI., 1992; Lebowitz, et aL, 1997; Lebowitz, Pea rson , & Cohen, 1998 ). In the aggrega te, th ey are more vulnerable to the hazards of pharmacothe rapy (Ca mpbell, 1991; Cumm in g, 1(98). Both pharmacokinetic and pharmacodynam ic d iffer­ e nces havc been descr ibed after psychotropic drugs are administered to ag in g ind iYiduals (&~rtz e t al.. 1997; Greenblatt, Harma tz, & Shader, 1991; 1991b; Nikai d o, Ellinwood , Heatherl y, & Gup ta , 1990; von Moltke, Greenb latt

Journal

Annual Review of Gerontology & GeriatricsSpringer Publishing

Published: Jan 1, 1999

There are no references for this article.