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Aging and Neoplasia

Aging and Neoplasia CHAPTER 1 JEFFREY CRAWFORD, M. D. * DIVISIONS OF HEMATOLOGY-ONCOLOGY AND GERIATRICS VETERANS ADMINISTRATION MEDICAL CENTER AND DUKE UNIVERSITY SCHOOL OF MEDICINE DURHAM, NORTH CAROLINA HARVEY JAY COHEN, M.D. DUKE UNIVERSITY CENTER FOR THE STUDY OF AGING AND HUMAN DEVEMPYENT GERIATRICS PROGRAMS, VETERANS ADMINISTRATION MEDICAL CENTER DURHAM, NORTH CAROLINA INTRODUCTION No statement about the need to explore the link between cancer ad aging speaks more strongly than the statistical relationship of these two phenomena. In the United States over one-half of all cancer occurs in the 11 percent of the population over age 65 (Butler and Gastel, 1979). This disproportionate degree of cancer in the elderly has been a continuing stimulus to research into the relationship between carcinogenesis and aging from the viewpoints of biochemistry, molecular genetics, immunology, nutrition, and hormonal influences, as applied to cell culture and animal models. In the clinical arena, however, insufficient time has been devoted to the approach to cancer in the elderly (Yancik et al., 'Work done during Veterans Administration Geriatric Fellowship, Durham, VAMC, and partially supported by a grant from the Mallinkrodt Foundation. 4 BIOLQGJCAL SCIENCES 1983). At age 25 the probability of developing cancer within 5 years is 1 in 700 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Gerontology & Geriatrics Springer Publishing

Aging and Neoplasia

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Publisher
Springer Publishing
ISSN
0198-8794
eISSN
1944-4036
DOI
10.1891/0198-8794.4.1.3
Publisher site
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Abstract

CHAPTER 1 JEFFREY CRAWFORD, M. D. * DIVISIONS OF HEMATOLOGY-ONCOLOGY AND GERIATRICS VETERANS ADMINISTRATION MEDICAL CENTER AND DUKE UNIVERSITY SCHOOL OF MEDICINE DURHAM, NORTH CAROLINA HARVEY JAY COHEN, M.D. DUKE UNIVERSITY CENTER FOR THE STUDY OF AGING AND HUMAN DEVEMPYENT GERIATRICS PROGRAMS, VETERANS ADMINISTRATION MEDICAL CENTER DURHAM, NORTH CAROLINA INTRODUCTION No statement about the need to explore the link between cancer ad aging speaks more strongly than the statistical relationship of these two phenomena. In the United States over one-half of all cancer occurs in the 11 percent of the population over age 65 (Butler and Gastel, 1979). This disproportionate degree of cancer in the elderly has been a continuing stimulus to research into the relationship between carcinogenesis and aging from the viewpoints of biochemistry, molecular genetics, immunology, nutrition, and hormonal influences, as applied to cell culture and animal models. In the clinical arena, however, insufficient time has been devoted to the approach to cancer in the elderly (Yancik et al., 'Work done during Veterans Administration Geriatric Fellowship, Durham, VAMC, and partially supported by a grant from the Mallinkrodt Foundation. 4 BIOLQGJCAL SCIENCES 1983). At age 25 the probability of developing cancer within 5 years is 1 in 700

Journal

Annual Review of Gerontology & Geriatrics – Springer Publishing

Published: Sep 1, 1984

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