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The Autism Diagnostic Observation Schedule (ADOS-2) is commonly used in the diagnosis of autism spectrum disorder (ASD). Although it has demonstrated good sensitivity and specificity in research settings, relatively little is known about its utility and accuracy in children and adolescents with co-occurring psychiatric disorders. We investigated this topic in children with acute psychiatric disorders. Our sample consisted of 58 patients, aged 9–18 years, admitted to a child and adolescent psychiatric inpatient unit with a suspected diagnosis of ASD. Both Modules 3 and 4 demonstrated low sensitivity (Module 3: 58.3%; Module 4: 55.6%) and specificity (Module 3: 56.5%; Module 4: 59.5%). These findings suggest that the ADOS-2 should be interpreted with caution while screening for autism in children with complex psychiatric disorders. Keywords Autism spectrum disorder (ASD) · Autism diagnostic observation schedule (ADOS-2) · Comorbidity · Psychiatric disorders Introduction be mistaken for other conditions, delaying its diagnosis and treatment [8]. Autism is a severe handicapping condition of early child- The diagnosis of autism is based on its core features hood consisting of social communication deficits with according to the DSM-5 [1] or the ICD-10 [9]. In addi- restricted interests and behaviors [1]. Currently classified as tion, several diagnostic instruments have been introduced a
European Child & Adolescent Psychiatry – Springer Journals
Published: Oct 5, 2019
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