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Utility of the ADOS-2 in children with psychiatric disorders

Utility of the ADOS-2 in children with psychiatric disorders The Autism Diagnostic Observation Schedule (ADOS-2) is commonly used in the diagnosis of autism spectrum disorder (ASD). Although it has demonstrated good sensitivity and specificity in research settings, relatively little is known about its utility and accuracy in children and adolescents with co-occurring psychiatric disorders. We investigated this topic in children with acute psychiatric disorders. Our sample consisted of 58 patients, aged 9–18 years, admitted to a child and adolescent psychiatric inpatient unit with a suspected diagnosis of ASD. Both Modules 3 and 4 demonstrated low sensitivity (Module 3: 58.3%; Module 4: 55.6%) and specificity (Module 3: 56.5%; Module 4: 59.5%). These findings suggest that the ADOS-2 should be interpreted with caution while screening for autism in children with complex psychiatric disorders. Keywords Autism spectrum disorder (ASD) · Autism diagnostic observation schedule (ADOS-2) · Comorbidity · Psychiatric disorders Introduction be mistaken for other conditions, delaying its diagnosis and treatment [8]. Autism is a severe handicapping condition of early child- The diagnosis of autism is based on its core features hood consisting of social communication deficits with according to the DSM-5 [1] or the ICD-10 [9]. In addi- restricted interests and behaviors [1]. Currently classified as tion, several diagnostic instruments have been introduced a http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Child & Adolescent Psychiatry Springer Journals

Utility of the ADOS-2 in children with psychiatric disorders

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References (23)

Publisher
Springer Journals
Copyright
Copyright © 2019 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Medicine & Public Health; Psychiatry; Child and Adolescent Psychiatry
ISSN
1018-8827
eISSN
1435-165X
DOI
10.1007/s00787-019-01411-8
Publisher site
See Article on Publisher Site

Abstract

The Autism Diagnostic Observation Schedule (ADOS-2) is commonly used in the diagnosis of autism spectrum disorder (ASD). Although it has demonstrated good sensitivity and specificity in research settings, relatively little is known about its utility and accuracy in children and adolescents with co-occurring psychiatric disorders. We investigated this topic in children with acute psychiatric disorders. Our sample consisted of 58 patients, aged 9–18 years, admitted to a child and adolescent psychiatric inpatient unit with a suspected diagnosis of ASD. Both Modules 3 and 4 demonstrated low sensitivity (Module 3: 58.3%; Module 4: 55.6%) and specificity (Module 3: 56.5%; Module 4: 59.5%). These findings suggest that the ADOS-2 should be interpreted with caution while screening for autism in children with complex psychiatric disorders. Keywords Autism spectrum disorder (ASD) · Autism diagnostic observation schedule (ADOS-2) · Comorbidity · Psychiatric disorders Introduction be mistaken for other conditions, delaying its diagnosis and treatment [8]. Autism is a severe handicapping condition of early child- The diagnosis of autism is based on its core features hood consisting of social communication deficits with according to the DSM-5 [1] or the ICD-10 [9]. In addi- restricted interests and behaviors [1]. Currently classified as tion, several diagnostic instruments have been introduced a

Journal

European Child & Adolescent PsychiatrySpringer Journals

Published: Oct 5, 2019

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