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Héctor Gonzalez, Elba Romero, A. Peregrina, T. Chávez, Estanislao Escobar-Islas, Lozano Felipe, C. Hoyo‐Vadillo (2003)
CYP2C19‐ and CYP3A4‐Dependent Omeprazole Metabolism in West MexicansThe Journal of Clinical Pharmacology, 43
A. Walan (1989)
Clinical experience with omeprazole: assessment of efficacy and safety.Journal of gastroenterology and hepatology, 4 Suppl 2
S. Wildt, G. Kearns, J. Leeder, J. Anker (1999)
Cytochrome P450 3AClinical Pharmacokinetics, 37
G. Tybring, Y. Böttiger, J. Widén, L. Bertilsson (1997)
Enantioselective hydroxylation of omeprazole catalyzed by CYP2C19 in Swedish white subjectsClinical Pharmacology & Therapeutics, 62
Y. Böttiger (2000)
Metabolic drug interactions in man : methodological aspects on in vivo studies
SN Wildt, GL Kearns, JS Leeder, JN Anker (1999)
Cytochrome P450 3A: ontogeny and drug dispositionClin Pharmacokin, 37
Tommy Andersson, C. Regårdh, M. Dahl‐Puustinen, Leif Bertilsson (1990)
Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.Therapeutic drug monitoring, 12 4
M. Christensen, K. Andersson, P. Dalén, R. Mirghani, G. Muirhead, A. Nordmark, G. Tybring, A. Wahlberg, Ü. Yaşar, L. Bertilsson (2003)
The karolinska cocktail for phenotyping of five human cytochrome P450 enzymesClinical Pharmacology & Therapeutics, 73
Y. Böttiger, G. Tybring, E. Götharson, L. Bertilsson (1997)
Inhibition of the sulfoxidation of omeprazole by ketoconazole in poor and extensive metabolizers of S‐mephenytoinClinical Pharmacology & Therapeutics, 62
Ming Chang, M. Dahl, G. Tybring, Eva Gotharson, L. Bertilsson (1995)
Use of omeprazole as a probe drug for CYP2C19 phenotype in Swedish Caucasians: comparison with S-mephenytoin hydroxylation phenotype and CYP2C19 genotype.Pharmacogenetics, 5 6
L. Bertilsson, Ya‐qing Lou, Yun-lei Du, Yin Liu, Tang‐Yun Kuang, Xia‐Mau Liao, Ke‐Yi Wang, J. Reviriego, L. Iselius, F. Sjöqvist (1992)
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S‐mephenytoinClinical Pharmacology & Therapeutics, 51
L. Bertilsson, G. Tybring, J. Widén, M. Chang, T. Tomson (2003)
Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19.British journal of clinical pharmacology, 44 2
K. Rost, I. Roots (1996)
Nonlinear kinetics after high‐dose omeprazole caused by saturation of genetically variable CYP2C19Hepatology, 23
Tommy Andersson, Tommy Andersson, J. Miners, M. Veronese, W. Tassaneeyakul, W. Tassaneeyakul, U. Meyer, D. Birkett (1993)
Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism.British journal of clinical pharmacology, 36 6
L Bertilsson, YQ Lou, YL Du, Y Liu, TY Kuang, XM Liao (1992)
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin [published erratum appears in Clin Pharmacol Ther 55(6):648]Clin Pharmacol Ther, 51
T. Shimada, H. Yamazaki, M. Mimura, Y. Inui, F. Guengerich (1994)
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.The Journal of pharmacology and experimental therapeutics, 270 1
N. Brynne, Y. Böttiger, B. Hallén, L. Bertilsson (1999)
Tolterodine does not affect the human in vivo metabolism of the probe drugs caffeine, debrisoquine and omeprazole.British journal of clinical pharmacology, 47 2
A single blood sample taken 3 h after intake of 20 mg of omeprazole can be reliably used to phenotype for both CYP2C19 and CYP3A4 activity.
European Journal of Clinical Pharmacology – Springer Journals
Published: Jun 22, 2006
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