Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Abel, D. Clody, L. Wennogle, Laurence Meyerson (1985)
Effect of chronic desmethylimipramine or electroconvulsive shock on selected brain and platelet neurotransmitter recognition sites.Biochemical pharmacology, 34 5
J. Marcusson, I. Bäckström, S. Ross (1986)
Single-site model of the neuronal 5-hydroxytryptamine uptake and imipramine-binding site.Molecular pharmacology, 30 2
A. Biegon (1986)
Effect of Chronic Desipramine Treatment on Dihydroalprenolol, Imipramine, and Desipramine Binding Sites: A Quantitative Autoradiographic Study in the Rat BrainJournal of Neurochemistry, 47
(1987)
5-HT sensitive [3H]lmapramine binding of protein nature in the human brain I: characteristics
(1984)
3H-Imipramine and 3Hcyano-imipramine binding in rat brain tissue: effect of longterm antidepressant administration
R. Raisman, M. Briley, S. Langer (1979)
Specific tricyclic antidepressant binding sites in rat brainNature, 281
C. Gentsch, M. Lichtsteiner, H. Feer (2005)
3H-imipramine and3H-cyano-imipramine binding in rat brain tissue: Effect of long-term antidepressant administrationJournal of Neural Transmission, 59
P. Hrdina (1984)
3H-Imipramine binding sites in brain down-regulated by chronic nortriptyline and haloperidol but not mianserin treatmentPsychiatry Research, 11
M. Wilson, E. Roy (1984)
Age alters the observed response of imipramine binding sites to chronic antidepressant treatment in female rats.European journal of pharmacology, 106 2
P. Plenge, E. Mellerup (2004)
3H-imipramine high-affinity binding sites in rat brain. Effects of imipramine and lithiumPsychopharmacology, 77
W. Kinnier, D. Chuang, E. Costa (1980)
Down regulation of dihydroalprenolol and imipramine binding sites in brain of rats repeatedly treated with imipramine.European journal of pharmacology, 67 2-3
M. Briley, R. Raisman, S. Arbilla, M. Casadamont, S. Langer (1982)
Concomitant decrease in [3H]imipramine binding in cat brain and platelets after chronic treatment with imipramine.European journal of pharmacology, 81 2
J. Marcusson, C. Fowler, H. Hall, S. Ross, B. Winblad (1985)
“Specific” Binding of [3H]Imipramine to Protease‐Sensitive and Protease‐Resistant SitesJournal of Neurochemistry, 44
M. Barbaccia, O. Gandolfi, D. Chuang, E. Costa (1983)
Modulation of neuronal serotonin uptake by a putative endogenous ligand of imipramine recognition sites.Proceedings of the National Academy of Sciences of the United States of America, 80 16
213 94 94 2 2 Jan Marcusson Inger T. Bäckström Svante B. Ross Department of Geriatric Medicine University of Ume» S901 87 Ume» Sweden Department of Pathology University of Ume» S-901 87 Ume» Sweden Department of Pharmacology Research and Developmental Laboratories Astra Alab AB S-151 85 Södertälje Sweden Abstract Several reports have shown heterogeneity of ( 3 H)imipramine binding to brain membranes. Recently, a high affinity and 5-HT sensitive ( 3 H)imipramine binding site of protein nature, that was suggested to be identical to the substrate recognition site for 5-HT uptake, was demonstrated. Since most studies on the regulation of the ( 3 H)imipramine binding sites by antidepressants have used desipramine displaceable binding, which is heterogenous in nature and contains binding not related to 5-HT uptake sites, the present report studies the possible effects of chronic (3 weeks) administration of imipramine or norzimeldine (10 mg/kg intraperitoneally twice daily) on 5-HT sensitive ( 3 H)imipramine binding sites. For comparison, desipramine sensitive binding was also studied, as well as the physiological correlate 5-HT uptake. There were no changes in either ( 3 H)imipramine binding or 5-HT uptake after the antidepressant treatment.
Psychopharmacology – Springer Journals
Published: Feb 1, 1988
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.