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K. Cantor, C. Lynch, M. Hildesheim, M. Dosemeci, J. Lubin, M. Alavanja, G. Craun (1998)
Drinking Water Source and Chlorination Byproducts I. Risk of Bladder CancerEpidemiology, 9
N. Künzli, I. Tager (1997)
The semi-individual study in air pollution epidemiology: a valid design as compared to ecologic studies.Environmental Health Perspectives, 105
T. Keegan, H. Whitaker, M. Nieuwenhuijsen, M. Toledano, P. Elliott, J. Fawell, M. Wilkinson, N. Best (2001)
Use of routinely collected data on trihalomethane in drinking water for epidemiological purposesOccupational and Environmental Medicine, 58
C. Lewis, I. Suffet, K. Hoggatt, B. Ritz (2005)
Malaria Vaccine Yields Parasite-Killing Antibodies in Human VolunteersPLoS Medicine, 2
Chun‐Yuh Yang, B. Cheng, S. Tsai, Trong-Neng Wu, Meng-Chiao Lin, Kuo-Cherng Lin (2000)
Association between chlorination of drinking water and adverse pregnancy outcome in Taiwan.Environmental Health Perspectives, 108
T. Zollinger, M. Przybylski, R. Gamache (2006)
Reliability of Indiana birth certificate data compared to medical records.Annals of epidemiology, 16 1
J. Grellier, J. Bennett, E. Patelarou, Rachel Smith, M. Toledano, L. Rushton, D. Briggs, M. Nieuwenhuijsen (2010)
Exposure to Disinfection By-products, Fetal Growth, and Prematurity: A Systematic Review and Meta-analysisEpidemiology, 21
S. Kaur, M. Nieuwenhuijsen, H. Ferrier, P. Steer (2004)
Exposure of pregnant women to tap water related activitiesOccupational and Environmental Medicine, 61
A. Hinckley, A. Bachand, J. Reif (2005)
Late Pregnancy Exposures to Disinfection By-products and Growth-Related Birth OutcomesEnvironmental Health Perspectives, 113
P. Singer, J. Barry, G. Palen, A. Scrivner (1981)
Trihalomethane formation in North Carolina drinking watersJournal American Water Works Association, 73
PM Doubilet, CB Benson, AS Nadel, SA Ringer (1997)
Improved birth weight table for neonates developed from gestations dated by early ultrasonographyJournal of Ultrasound in Medicine, 16
Chun-Yuh Yang, Zhi-Ping Xiao, Shu Ho, Trong-Neng Wu, S. Tsai (2007)
Association between trihalomethane concentrations in drinking water and adverse pregnancy outcome in Taiwan.Environmental research, 104 3
D. Savitz, K. Andrews, L. Pastore (1995)
Drinking water and pregnancy outcome in central North Carolina: source, amount, and trihalomethane levels.Environmental Health Perspectives, 103
David DiGiuseppe, D. Aron, Lorin Ranbom, D. Harper, G. Rosenthal (2002)
Reliability of Birth Certificate Data: A Multi-Hospital Comparison to Medical Records InformationMaternal and Child Health Journal, 6
W. Holden (1970)
Water treatment and examination
R. Tardiff, M. Carson, M. Ginevan (2006)
Updated weight of evidence for an association between adverse reproductive and developmental effects and exposure to disinfection by-products.Regulatory toxicology and pharmacology : RTP, 45 2
M. Nieuwenhuijsen, M. Toledano, N. Eaton, J. Fawell, P. Elliott (2000)
Chlorination disinfection byproducts in water and their association with adverse reproductive outcomes: a reviewOccupational and Environmental Medicine, 57
Caroline Hoffman, P. Mendola, D. Savitz, A. Herring, D. Loomis, K. Hartmann, P. Singer, H. Weinberg, A. Olshan (2008)
Drinking Water Disinfection By-Product Exposure and Fetal GrowthEpidemiology, 19
C. Porter, S. Putnam, K. Hunting, M. Riddle (2005)
The effect of trihalomethane and haloacetic acid exposure on fetal growth in a Maryland county.American journal of epidemiology, 162 4
C. Weisel, W. Jo (1996)
Ingestion, inhalation, and dermal exposures to chloroform and trichloroethene from tap water.Environmental Health Perspectives, 104
C. Lewis, I. Suffet, B. Ritz (2006)
Estimated effects of disinfection by-products on birth weight in a population served by a single water utility.American journal of epidemiology, 163 1
J. Wright, J. Schwartz, Douglas Dockery (2004)
The effect of disinfection by-products and mutagenic activity on birth weight and gestational duration.Environmental Health Perspectives, 112
L. Vinikoor, L. Messer, B. Laraia, J. Kaufman (2010)
Reliability of variables on the North Carolina birth certificate: a comparison with directly queried values from a cohort study.Paediatric and perinatal epidemiology, 24 1
F. Bové, Youn Shim, P. Zeitz (2002)
Drinking water contaminants and adverse pregnancy outcomes: a review.Environmental Health Perspectives, 110
Eleni Malliarou, C. Collins, N. Graham, M. Nieuwenhuijsen (2005)
Haloacetic acids in drinking water in the United Kingdom.Water research, 39 12
C Lewis, IH Suffet, K Hoggatt, B Ritz (2007)
Estimated effects of disinfection by-products on preterm birth in a population served by a single water utilityEnvironmental Health Perspectives, 115
H. Whitaker, M. Nieuwenhuijsen, N. Best (2002)
The relationship between water concentrations and individual uptake of chloroform: a simulation study.Environmental Health Perspectives, 111
C. Moudgal, J. Lipscomb, R. Bruce (2000)
Potential health effects of drinking water disinfection by-products using quantitative structure toxicity relationship.Toxicology, 147 2
M. Toledano, M. Nieuwenhuijsen, N. Best, H. Whitaker, P. Hambly, C. Hoogh, J. Fawell, L. Jarup, P. Elliott (2004)
Relation of Trihalomethane Concentrations in Public Water Supplies to Stillbirth and Birth Weight in Three Water Regions in EnglandEnvironmental Health Perspectives, 113
K. Waller, S. Swan, G. Delorenze, Barbara Hopkins (1998)
Trihalomethanes in Drinking Water and Spontaneous AbortionEpidemiology, 9
Caroline Hoffman, P. Mendola, D. Savitz, A. Herring, D. Loomis, K. Hartmann, P. Singer, H. Weinberg, A. Olshan (2008)
Drinking Water Disinfection By-Product Exposure and Duration of GestationEpidemiology, 19
L. Dodds, W. King, C. Woolcott, J. Pole (1999)
Trihalomethanes in public water supplies and adverse birth outcomes.Epidemiology, 10 3
W. King, L. Marrett (1996)
Case-control study of bladder cancer and chlorination by-products in treated water (Ontario, Canada)Cancer Causes & Control, 7
M. Kramer, C. Lynch, P. Isacson, J. Hanson (1992)
The Association of Waterborne Chloroform with Intrauterine Growth RetardationEpidemiology, 3
F. Murray, B. Schwetz, J. Mcbride, R. Staples (1979)
Toxicity of inhaled chloroform in pregnant mice and their offspring.Toxicology and applied pharmacology, 50 3
B. Schwetz, B. Leong, P. Gehring (1974)
Embryo- and fetotoxicity of inhaled chloroform in rats.Toxicology and applied pharmacology, 28 3
F. Bové, M. Fulcomer, J. Klotz, Jorge Esmart, Ellen Dufficy, J. Savrin (1995)
Public drinking water contamination and birth outcomes.American journal of epidemiology, 141 9
D. Thompson, S. Warner, V. Robinson (1974)
Teratology studies on orally administered chloroform in the rat and rabbit.Toxicology and applied pharmacology, 29 3
D. Fell, L. Dodds, W. King (2004)
Residential mobility during pregnancy.Paediatric and perinatal epidemiology, 18 6
G. Britton, JoAnne Brinthaupt, Joyce Stehle, G. James (2004)
Comparison of self-reported smoking and urinary cotinine levels in a rural pregnant population.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 33 3
P. Magnus, J. Jaakkola, A. Skrondal, J. Alexander, Georg Becker, T. Krogh, E. Dybing (1999)
Water chlorination and birth defects.Epidemiology, 10 5
KP Cantor, CF Lynch, ME Hildesheim, M Dosemeci, J Lubin, M Alavanja, GF Craun (1998)
Drinking water source and chlorination byproducts in Iowa. Ill: Risk of bladder cancerEpidemiology, 9
W. King, L. Dodds, B. Armson, A. Allen, D. Fell, C. Nimrod (2004)
Exposure assessment in epidemiologic studies of adverse pregnancy outcomes and disinfection byproductsJournal of Exposure Analysis and Environmental Epidemiology, 14
M. Aliyu, Roneé Wilson, R. Zoorob, K. Brown, A. Alio, H. Clayton, H. Salihu (2009)
Prenatal alcohol consumption and fetal growth restriction: potentiation effect by concomitant smoking.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 11 1
M. Gallagher, J. Nuckols, L. Stallones, David Savitzl (1998)
Exposure to Trihalomethanes and Adverse Pregnancy OutcomesEpidemiology, 9
J. Ruddick, D. Villeneuve, I. Chu, V. Valli (1983)
A teratological assessment of four trihalomethanes in the rat.Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 18 3
Assia Miller, C. Siffel, A. Correa (2010)
Residential Mobility During Pregnancy: Patterns and CorrelatesMaternal and Child Health Journal, 14
K. Cantor, Charles Lynch, Mariana Hildesheim, M. Dosemeci, Jay Lubin, Michael Alavanja, GUNTHER Craun (1999)
Drinking water source and chlorination byproducts in Iowa. III. Risk of brain cancer.American journal of epidemiology, 150 6
J. Rook (1974)
Formation of Haloforms during Chlorination of natural Waters, 23
C. Graves, G. Matanoski, R. Tardiff (2001)
Weight of evidence for an association between adverse reproductive and developmental effects and exposure to disinfection by-products: a critical review.Regulatory toxicology and pharmacology : RTP, 34 2
G. Alexander, J. Himes, Rajni Kaufman, J. Mor, Michael Kogan (1996)
A United States National Reference for Fetal GrowthObstetrics & Gynecology, 87
J. Wright, J. Schwartz, D. Dockery (2003)
Effect of trihalomethane exposure on fetal developmentOccupational and Environmental Medicine, 60
P. Lilly, Tracey Ross, Rex Pegramt (1997)
Trihalomethane comparative toxicity: acute renal and hepatic toxicity of chloroform and bromodichloromethane following aqueous gavage.Fundamental and applied toxicology : official journal of the Society of Toxicology, 40 1
M. Kotelchuck (1994)
An evaluation of the Kessner Adequacy of Prenatal Care Index and a proposed Adequacy of Prenatal Care Utilization Index.American journal of public health, 84 9
P. Doubilet, C. Benson, A. Nadel, S. Ringer (1997)
Improved Birth Weight Table for Neonates Developed from Gestations Dated by Early UltrasonographyJournal of Diagnostic Medical Sonography, 13
M. Kramer (1987)
Intrauterine growth and gestational duration determinants.Pediatrics, 80 4
Gary Dr.P.H., Lorraine M.P.H. (1991)
Residential mobility during pregnancy for mothers of infants with or without congenital cardiac anomalies: a reprint.Archives of Environmental Health, 47
Reproductive effects of long-term, low-dose exposure to disinfectant by-products have not been consistently documented in large populations despite the known toxicity of high exposures and the wide-spread occurrence of low concentrations in public drinking water. We investigated the effect of low-dose exposure to total trihalomethanes (TTHM) on birth weight and gestational term in New York State. All singleton live births from 1998 through 2003 in 62 counties in New York State were linked with public water supply (PWS) system boundaries based on mother’s residential address on birth certificate. Using the data from public water supply system, TTHM measurements were assigned geographically and temporally to each birth record linked with PWS boundary. Individual level maternal information including mother’s race, ethnicity, education, employment status, smoking, age, along with adequacy of prenatal care utilization and infant’s gender was used in a logistic model to adjust for potential confounding. A small non-linear association was detected between TTHM exposure and low birth weight (<2,500 g) births (OR 1.14; 95 % confidence interval (CI) 1.08–1.21), preterm births (OR 1.14; 95 % CI 1.08–1.20) and for small for gestational age births (OR 1.10; 95 % CI 1.04–1.16) suggesting a small increase in risk for these birth outcomes with chronic low maternal exposure to drinking water containing trihalomethanes. Maternal exposure to TTHMs during pregnancy may be associated with low birth weight, preterm births and small for gestational age births.
Maternal and Child Health Journal – Springer Journals
Published: Jul 25, 2013
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