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The synthesis of Aspirin and Acetobromo-α-D-glucose using 3D printed flow reactors: an undergraduate demonstration

The synthesis of Aspirin and Acetobromo-α-D-glucose using 3D printed flow reactors: an... The field of flow chemistry is growing rapidly, drawing attention across different disciplines. Despite its increasing popularity in the industry and research, little attention is given to the teaching of flow chemistry in the educational environment, especially at the undergraduate level. A major challenge with teaching undergraduate flow chemistry is the high cost of flow chemistry equipment. This study reports the development of low-cost, functioning flow chemistry equipment for the teaching of flow chemistry and experimental practicum. This provides the students with hands-on instruction in fabricating flow reaction devices by 3D printing. It also allows undergraduate students to understand the basics of flow chemistry and chemical engineering. An exciting part of this study is the skills acquired by undergraduate students. This is because of the learning experience they are exposed to by training and independently operating fabrication equipment, setting up flow experiments and conducting flow experiments with the fabricated devices. Finally, due to the low cost of the equipment, the set-up is suitable for teaching flow chemistry in a low-resource environment, such as our teaching laboratories in South Africa.Graphical abstract[graphic not available: see fulltext] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Flow Chemistry Springer Journals

The synthesis of Aspirin and Acetobromo-α-D-glucose using 3D printed flow reactors: an undergraduate demonstration

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Publisher
Springer Journals
Copyright
Copyright © Akadémiai Kiadó 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
ISSN
2062-249X
eISSN
2063-0212
DOI
10.1007/s41981-022-00236-y
Publisher site
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Abstract

The field of flow chemistry is growing rapidly, drawing attention across different disciplines. Despite its increasing popularity in the industry and research, little attention is given to the teaching of flow chemistry in the educational environment, especially at the undergraduate level. A major challenge with teaching undergraduate flow chemistry is the high cost of flow chemistry equipment. This study reports the development of low-cost, functioning flow chemistry equipment for the teaching of flow chemistry and experimental practicum. This provides the students with hands-on instruction in fabricating flow reaction devices by 3D printing. It also allows undergraduate students to understand the basics of flow chemistry and chemical engineering. An exciting part of this study is the skills acquired by undergraduate students. This is because of the learning experience they are exposed to by training and independently operating fabrication equipment, setting up flow experiments and conducting flow experiments with the fabricated devices. Finally, due to the low cost of the equipment, the set-up is suitable for teaching flow chemistry in a low-resource environment, such as our teaching laboratories in South Africa.Graphical abstract[graphic not available: see fulltext]

Journal

Journal of Flow Chemistry – Springer Journals

Published: Sep 1, 2022

Keywords: Flow chemistry; 3D printing; Reaction devices; Catalysis; Undergraduate students

References

  • Continuous flow reactor Technology for Nanomaterial Synthesis
    Watts, P
  • Micro reactors, flow reactors and continuous flow synthesis
    Watts, P; Wiles, C
  • Continuous-flow chemistry in chemical education
    Blanco-Ania, D; Rutjes, FPJT
  • Current and future trends of additive manufacturing for chemistry applications: a review
    Alimi, OA; Meijboom, R
  • Homemade 3-D printed flow reactors for heterogeneous catalysis
    Alimi, OA; Bingwa, N; Meijboom, R
  • Design and fabrication of a monolith catalyst for continuous flow epoxidation of styrene in polypropylene printed flow reactor
    Alimi, OA; Ncongwane, TB; Meijboom, R
  • 3-D printed microreactor for continuous flow oxidation of a flavonoid
    Alimi, OA; Akinnawo, CA; Onisuru, OR; Meijboom, R
  • Continuous-flow catalytic degradation of Hexacyanoferrate ion through Electron transfer induction in a 3D-printed flow reactor
    Onisuru, OR; Alimi, OA; Potgieter, K; Meijboom, R
  • Monolith catalyst design via 3D printing: a reusable support for modern palladium-catalyzed cross-coupling reactions
    Alimi, OA; Akinnawo, CA; Meijboom, R
  • Trapping shape-controlled nanoparticle nucleation and growth stages via continuous-flow chemistry
    LaGrow, AP; Besong, TMD; AlYami, NM
  • Flow photochemistry: Shine some light on those tubes!
    Sambiagio, C; Noël, T
  • The fundamentals behind the use of flow reactors in electrochemistry
    Noël, T; Cao, Y; Laudadio, G
  • Flow electrolysis cells for the synthetic organic chemistry laboratory
    Pletcher, D; Green, RA; Brown, RCD
  • Flow chemistry in undergraduate organic chemistry education
    König, B; Kreitmeier, P; Hilgers, P; Wirth, T
  • Extending practical flow chemistry into the undergraduate curriculum via the use of a portable low-cost 3D printed continuous flow system
    Penny, MR; Tsui, N; Hilton, ST
  • A gentle introduction to the noble art of flow chemistry
    Bannock, JH; Krishnadasan, SH; Heeney, M; de Mello, JC
  • Continuous flow science in an undergraduate teaching laboratory: bleach-mediated oxidation in a biphasic system
    Kairouz, V; Collins, SK
  • Integrated microreactors for reaction automation: new approaches to reaction development
    McMullen, JP; Jensen, KF
  • Methylation of 2-naphthol using dimethyl carbonate under continuous-flow gas-phase conditions
    Tundo, P; Rosamilia, AE; Arico, F
  • 3D-printed microfluidics for hands-on undergraduate laboratory experiments
    Vangunten, MT; Walker, UJ; Do, HG; Knust, KN
  • Continuous-flow chemistry in undergraduate education: sustainable conversion of reclaimed vegetable oil into biodiesel
    Leibfarth, FA; Russell, MG; Langley, DM
  • An open source toolkit for 3D printed fluidics
    Price, AJN; Capel, AJ; Lee, RJ
  • Flow chemistry experiments in the undergraduate teaching laboratory: synthesis of diazo dyes and disulfides
    Kuijpers, KPL; Weggemans, WMA; Verwijlen, CJA; Noël, T
  • Behavior of capillary valves in centrifugal microfluidic devices prepared by three-dimensional printing
    Moore, JL; McCuiston, A; Mittendorf, I
  • Low-budget 3D-printed equipment for continuous flow reactions
    Neumaier, JM; Madani, A; Klein, T; Ziegler, T
  • Principles of open source bioinstrumentation applied to the poseidon syringe pump system
    Booeshaghi, AS; da Veiga, BE; Bannon, D
  • Synthesis of aspirin: a general chemistry experiment
    Olmsted, JA
  • True melting point determination
    Young, JC
  • Experiments with aspirin
    Barry, E; Borer, LL
  • Involvement of salicylic acid and other phenolic compounds in light-dependent cold acclimation in maize
    Pál, M; Janda, T; Majláth, I; Szalai, G
  • A simple preparation of 2, 3, 4, 6-tetra-O-acyl-gluco-, galacto-and mannopyranoses and relevant theoretical study
    Wang, ZD; Mo, Y; Chiou, C-L; Liu, M
  • Comparative study of the synthesis of silica nanoparticles in micromixer–microreactor and batch reactor systems
    Gutierrez, L; Gomez, L; Irusta, S