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The incidence of plasma insulin, blood sugar and serum lipid abnormalities in patients with atherosclerotic disease

The incidence of plasma insulin, blood sugar and serum lipid abnormalities in patients with... 125 7 7 6 6 J. M. Sloan M.D. J. S. Mackay B. Sheridan Royal Victoria Hospital Belfast 12 N. Ireland Pathology Dept. University of Sheffield S 10 2TN Sheffield Yorkshire England Summary The incidence of abnormalities of fasting serum cholesterol and triglyceride levels and blood sugar and plasma insulin response to an oral glucose load have been investigated in a group of 51 male patients with atherosclerotic peripheral vascular disease. These have been compared with an age and sex matched group of 47 healthy controls. Both groups showed a similar degree of obesity. The most common single abnormality was a prolonged and increased plasma insulin response, which was much more frequently seen among patients than controls. Over 75% of the patients showed abnormality of blood sugar or insulin response. Elevation of fasting levels of serum lipids was considerably less common, although the mean serum cholesterol level of the patients was significantly higher than that of the controls. The relevance of these results is discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetologia Springer Journals

The incidence of plasma insulin, blood sugar and serum lipid abnormalities in patients with atherosclerotic disease

Diabetologia , Volume 7 (6) – Dec 1, 1971

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References (17)

Publisher
Springer Journals
Copyright
Copyright © 1971 by Springer-Verlag
Subject
Medicine & Public Health; Human Physiology; Internal Medicine; Metabolic Diseases
ISSN
0012-186X
eISSN
1432-0428
DOI
10.1007/BF01212058
Publisher site
See Article on Publisher Site

Abstract

125 7 7 6 6 J. M. Sloan M.D. J. S. Mackay B. Sheridan Royal Victoria Hospital Belfast 12 N. Ireland Pathology Dept. University of Sheffield S 10 2TN Sheffield Yorkshire England Summary The incidence of abnormalities of fasting serum cholesterol and triglyceride levels and blood sugar and plasma insulin response to an oral glucose load have been investigated in a group of 51 male patients with atherosclerotic peripheral vascular disease. These have been compared with an age and sex matched group of 47 healthy controls. Both groups showed a similar degree of obesity. The most common single abnormality was a prolonged and increased plasma insulin response, which was much more frequently seen among patients than controls. Over 75% of the patients showed abnormality of blood sugar or insulin response. Elevation of fasting levels of serum lipids was considerably less common, although the mean serum cholesterol level of the patients was significantly higher than that of the controls. The relevance of these results is discussed.

Journal

DiabetologiaSpringer Journals

Published: Dec 1, 1971

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