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The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism

The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism The purpose of this presentation is to review the current state of knowledge regarding 5,8,11,14-eicosatetraynoic acid (ETYA, Ro 3-1428) and its effects on lipid metabolism. Accordingly, the topics discussed include hypocholesterolemic and dermatological studies involving ETYA in both animals and man, as well as the effects of ETYA on desaturate enzymes. Metabolic studies involving ETYA are also noted. Primary interest is focused on the effects of ETYA on selected processes of arachidonate metabolism, and the effect of ETYA on inflammation, platelet aggregation and tumor growth are discussed, keeping in mind the relevance of arachidonate metabolism to these processes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Lipids Springer Journals

The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism

Lipids , Volume 14 (2) – Feb 1, 1979

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Publisher
Springer Journals
Copyright
Copyright © 1979 by American Oil Chemists’ Society
Subject
Life Sciences; Nutrition; Bioorganic Chemistry; Medicinal Chemistry; Medical Biochemistry; Biochemistry, general; Microbial Genetics and Genomics
ISSN
0024-4201
eISSN
1558-9307
DOI
10.1007/BF02533870
Publisher site
See Article on Publisher Site

Abstract

The purpose of this presentation is to review the current state of knowledge regarding 5,8,11,14-eicosatetraynoic acid (ETYA, Ro 3-1428) and its effects on lipid metabolism. Accordingly, the topics discussed include hypocholesterolemic and dermatological studies involving ETYA in both animals and man, as well as the effects of ETYA on desaturate enzymes. Metabolic studies involving ETYA are also noted. Primary interest is focused on the effects of ETYA on selected processes of arachidonate metabolism, and the effect of ETYA on inflammation, platelet aggregation and tumor growth are discussed, keeping in mind the relevance of arachidonate metabolism to these processes.

Journal

LipidsSpringer Journals

Published: Feb 1, 1979

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