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Sex Differences in Animal Models of Opioid Reward

Sex Differences in Animal Models of Opioid Reward Purpose of ReviewThis review aims to discuss sex differences observed in preclinical rodent models of opioid reward.Recent FindingsUtilizing a variety of methodological approaches and drug regimens, no clear consensus has emerged regarding the effects of opiates between males and females. This is quite dissimilar to work examining psychostimulants, where female animals reliably exhibit stronger behavioral responses.SummaryWith opioid research quickly expanding to determine the neural underpinnings of opioid addiction, further research is essential to determine the conditions wherein sex differences may occur and how they may relate to the human condition. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Sexual Health Reports Springer Journals

Sex Differences in Animal Models of Opioid Reward

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Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2020
ISSN
1548-3584
eISSN
1548-3592
DOI
10.1007/s11930-020-00266-4
Publisher site
See Article on Publisher Site

Abstract

Purpose of ReviewThis review aims to discuss sex differences observed in preclinical rodent models of opioid reward.Recent FindingsUtilizing a variety of methodological approaches and drug regimens, no clear consensus has emerged regarding the effects of opiates between males and females. This is quite dissimilar to work examining psychostimulants, where female animals reliably exhibit stronger behavioral responses.SummaryWith opioid research quickly expanding to determine the neural underpinnings of opioid addiction, further research is essential to determine the conditions wherein sex differences may occur and how they may relate to the human condition.

Journal

Current Sexual Health ReportsSpringer Journals

Published: Sep 17, 2020

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