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Rubidium-induced increase in shock-elicited aggression in rats

Rubidium-induced increase in shock-elicited aggression in rats 213 22 22 3 3 Jon M. Stolk Robert L. Conner Jack D. Barchas Department of Psychiatry Stanford University School of Medicine 94305 Stanford California Abstract Daily treatment of rats with 0.3 or 0.6 meq/kg rubidium chloride (RbCl) causes an increase in shock-elicited aggressive behavior relative to potassium chloride-treated controls. Aggressive responses increase immediately with the higher dose of RbCl and are maintained for 12 days. The lower RbCl dosage increases fighting behavior significantly after 11 consecutive injection days. Measurements of flinch, jump, and vocalization threshold reveal no consistent pattern with treatment; thus, it is unlikely that threshold changes underlie the observed increases in aggression. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Rubidium-induced increase in shock-elicited aggression in rats

Psychopharmacology , Volume 22 (3) – Sep 1, 1971

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References (23)

Publisher
Springer Journals
Copyright
Copyright © 1971 by Springer-Verlag
Subject
Biomedicine; Pharmacology/Toxicology; Psychiatry
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/BF00401787
Publisher site
See Article on Publisher Site

Abstract

213 22 22 3 3 Jon M. Stolk Robert L. Conner Jack D. Barchas Department of Psychiatry Stanford University School of Medicine 94305 Stanford California Abstract Daily treatment of rats with 0.3 or 0.6 meq/kg rubidium chloride (RbCl) causes an increase in shock-elicited aggressive behavior relative to potassium chloride-treated controls. Aggressive responses increase immediately with the higher dose of RbCl and are maintained for 12 days. The lower RbCl dosage increases fighting behavior significantly after 11 consecutive injection days. Measurements of flinch, jump, and vocalization threshold reveal no consistent pattern with treatment; thus, it is unlikely that threshold changes underlie the observed increases in aggression.

Journal

PsychopharmacologySpringer Journals

Published: Sep 1, 1971

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