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Reply Pediatr Radiol (2006) 36: 1330 DOI 10.1007/s00247-006-0310-3 LETTER TO THE EDITOR . . Zarazuela Zolkipli Hisham Dahmoush . . Dawn Saunders W.K. Chong Robert Surtees Received: 7 July 2006 / Accepted: 9 July 2006 / Published online: 7 October 2006 # Springer-Verlag 2006 Sir, to myelinated white matter is a necessary requirement for the Thank you for the prompt response from Susan Hayflick eye-of-the-tiger sign and see no evidence of this. The and Shawn Westaway to our report on a pair of siblings differential diagnosis of the appearance in Fig. 1 is wide in with PANK2 mutation who did not show the “eye-of-the- children because many conditions apart from PANK are well- tiger” sign on T2-weighted MR imaging. recognised causes of such appearances. These include In response to their first point on Fig. 1, our neuro- methylmalonic acidaemia and carbon monoxide poisoning. radiological opinion differs from theirs because we do not Hayflick and Westaway may not have much experience with agree that it shows the eye-of-the-tiger sign. It is important to these other causes. point out firstly that descriptions regarding hypo-, iso- or In response to their point on Fig. 2, as discussed in our hyperintensity of any structure http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Radiology Springer Journals

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Pediatr Radiol (2006) 36: 1330 DOI 10.1007/s00247-006-0310-3 LETTER TO THE EDITOR . . Zarazuela Zolkipli Hisham Dahmoush . . Dawn Saunders W.K. Chong Robert Surtees Received: 7 July 2006 / Accepted: 9 July 2006 / Published online: 7 October 2006 # Springer-Verlag 2006 Sir, to myelinated white matter is a necessary requirement for the Thank you for the prompt response from Susan Hayflick eye-of-the-tiger sign and see no evidence of this. The and Shawn Westaway to our report on a pair of...
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Publisher
Springer Journals
Copyright
Copyright © 2006 by Springer-Verlag
Subject
Medicine & Public Health; Oncology ; Ultrasound; Nuclear Medicine ; Neuroradiology ; Pediatrics ; Imaging / Radiology
ISSN
0301-0449
eISSN
1432-1998
DOI
10.1007/s00247-006-0310-3
Publisher site
See Article on Publisher Site

Abstract

Pediatr Radiol (2006) 36: 1330 DOI 10.1007/s00247-006-0310-3 LETTER TO THE EDITOR . . Zarazuela Zolkipli Hisham Dahmoush . . Dawn Saunders W.K. Chong Robert Surtees Received: 7 July 2006 / Accepted: 9 July 2006 / Published online: 7 October 2006 # Springer-Verlag 2006 Sir, to myelinated white matter is a necessary requirement for the Thank you for the prompt response from Susan Hayflick eye-of-the-tiger sign and see no evidence of this. The and Shawn Westaway to our report on a pair of siblings differential diagnosis of the appearance in Fig. 1 is wide in with PANK2 mutation who did not show the “eye-of-the- children because many conditions apart from PANK are well- tiger” sign on T2-weighted MR imaging. recognised causes of such appearances. These include In response to their first point on Fig. 1, our neuro- methylmalonic acidaemia and carbon monoxide poisoning. radiological opinion differs from theirs because we do not Hayflick and Westaway may not have much experience with agree that it shows the eye-of-the-tiger sign. It is important to these other causes. point out firstly that descriptions regarding hypo-, iso- or In response to their point on Fig. 2, as discussed in our hyperintensity of any structure

Journal

Pediatric RadiologySpringer Journals

Published: Oct 7, 2006

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