Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Dehaye, J. Winand, J. Christophe (1978)
Adenylate cyclase activity in the epididymal adipose tissue from obese-hyperglycaemic miceDiabetologia, 15
(1957)
Eine enzymatische Méthode zur Bestimmung von Glycerol
The effects of epinephrine and insulin on the control of lipase , phosphorylase kinase , phosphorylase and glycogen synthetase
J. Dehaye, J. Winand, Jean Christophe (1977)
Lipolysis and cyclic AMP levels in epididymal adipose tissue of obese-hyperglycaemic miceDiabetologia, 13
(1977)
Calcium and lipolysis in adipose tissue : effects of ethanedioxybis - ( ethylamine ) tetra - acetate ( EGTA ) and ionophore A 23187
K. Siddle, C. Hales (1974)
The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic monophosphate content in isolated rat fat-cells.The Biochemical journal, 142 2
I. Bihler, B. Jeanrenaud (1970)
ATP content of isolated fat cells. Effects of insulin, ouabain, and lipolytic agents.Biochimica et biophysica acta, 202 3
(1976)
Effect of preincubation on the metabolism of [ U - 14 C ] glucose and [ 3 H ] H 20 by the epididymal adipose tissue of obesehyperglycemic ( ob / ob ) Bar Harbor mice
(1973)
Hor - monal regulation of adipocyte enzymes . The effects of epinephrine and insulin on the control of lipase , phosphorylase kinase , phosphorylase and glycogen synthetase
Jørgen Gliemann, K. Østerlind, Jørgen Vinten, Steen Gammeltoft (1972)
A procedure for measurement of distribution spaces in isolated fat cells.Biochimica et biophysica acta, 286 1
P. Belfrage, Bengt Jergil, Peter Strålfors, Hans Tornqvist (1977)
Hormone‐sensitive lipase of rat adipose tissue: Identification and some properties of the enzyme proteinFEBS Letters, 75
(1967)
Mrtabolisme in vitro du tissu adipeux . IV . Relations entre les espaces aqueux du tissu adipeux 4 pididymaire du rat et l ' albumine s 4 rique
B. Mosinger, Martha Vaughan (1967)
Effects of electrolytes on epinephrine stimulated lipolysis in adipose tissue in vitro.Biochimica et biophysica acta, 144 3
T. Clausen (1970)
Electrolytes and the hormonal control of organic metabolism in adipocytes.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2
K. Siddle, C. Hales (1977)
Calcium and lipolysis in adipose tissue: effects of ethanedioxybis-(ethylamine)tetra-acetate (EGTA) and ionophore A23187 [proceedings].Biochemical Society transactions, 5 4
Aubie Angel, K. Desai, Mitchell Halperin (1971)
Reduction in adipocyte ATP by lipolytic agents: relation to intracellular free fatty acid accumulation.Journal of lipid research, 12 2
A. Kissebah, P. Clarke, N. Vydelingum, H. Hope-Gill, B. Tulloch, T. Fraser (1975)
The Role of Calcium in Insulin ActionEuropean Journal of Clinical Investigation, 5
S. Akgun, D. Rudman (1969)
Relationships between mobilization of free fatty acids from adipose tissue, and the concentrations of calcium in the extracellular fluid and in the tissue.Endocrinology, 84 4
O. Crofford, A. Renold (1965)
GLUCOSE UPTAKE BY INCUBATED RAT EPIDIDYMAL ADIPOSE TISSUE. RATE-LIMITING STEPS AND SITE OF INSULIN ACTION.The Journal of biological chemistry, 240
R. Schimmel (1973)
The influence of extracellular calcium ion on hormone-activated lipolysis.Biochimica et biophysica acta, 326 2
A. Katocs, E. Largis, D. Allen (1974)
Role of Ca2+ in adrenocorticotropic hormone-stimulated lipolysis in the perfused fat cell system.The Journal of biological chemistry, 249 7
A. Gilman (1970)
A protein binding assay for adenosine 3':5'-cyclic monophosphate.Proceedings of the National Academy of Sciences of the United States of America, 67 1
J. Dehaye, J. Winand, J. Christophe (1977)
Effect of lipolytic agents on calcium uptake in the epididymal adipose tissue of obese-hyperglycemic mice and their lean controls [proceedings].Archives internationales de physiologie et de biochimie, 85 2
D. Bruns, J. McDonald, L. Jarett (1976)
Energy-dependent calcium transport in endoplasmic reticulum of adipocytes.The Journal of biological chemistry, 251 22
S. Efendić, B. Alm, H. Löw (1970)
Effects of Ca++ on Lipolysis in Human Omental Adipose Tissue In VitroHormone and Metabolic Research, 2
D. Severson, R. Denton, B. Bridges, P. Randle (1976)
Exchangeable and total calcium pools in mitochondria of rat epididymal fat-pads and isolated fat-cells. Role in the regulation of pyruvate dehydrogenase activity.The Biochemical journal, 154 1
(1978)
Adenylate cyclase activity in the epididymal adipose tissue from obese - hypergly - caemic mice
(1976)
Exchangeable and total calcium pools in mitochondria of rat epididymal fatpads and isolated fatcells
Ulrich Schwabe, R. Ebert (2004)
Different effects of lipolytic hormones and phosphodiesterase inhibitors on cyclic 3′,5′-AMP levels in isolated fat cellsNaunyn-Schmiedeberg's Archives of Pharmacology, 274
P. Freychet, M. Laudat, P. Laudat, G. Rosselin, C. Kahn, P. Gorden, J. Roth (1972)
Impairment of insulin binding to the fat cell plasma membrane in the obese hyperglycemic mouseFEBS Letters, 25
D. Hems, G. Ma (1976)
Resistance to hepatic action of vasopressin in genetically obese (ob/ob) mice.The Biochemical journal, 160 1
R. Shepherd, C. Malbon, C. Smith, J. Fain (1977)
Lipolysis and adenosine 3':5'-monophosphate metabolism in isolated white fat cells from genetically obese-hyperglycemic mice (ob/ob).The Journal of biological chemistry, 252 20
J. Fain (1973)
Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by adenosine, N6-(phenylisopropyl) adenosine, and related compounds.Molecular pharmacology, 9 5
D. York, G. Bray, Y. Yukimura (1978)
An enzymatic defect in the obese (ob/ob) mouse: loss of thyroid-induced sodium- and potassium-dependent adenosinetriphosphatase.Proceedings of the National Academy of Sciences of the United States of America, 75 1
H. Hope-Gill, A. Kissebah, B. Tulloch, P. Clarke, N. Vydelingum, T. Fraser (1975)
The Effects of Insulin on Adipocyte Calcium Flux and the Interaction with the Effects of Dibutyryl Cyclic AMP and AdrenalineHormone and Metabolic Research, 7
B. Martin, T. Clausen, J. Gliemann (1975)
Relationships between the exchange of calcium and phosphate in isolated fat-cells.The Biochemical journal, 152 1
C. Breemen, Blanca Farinas, R. Casteels, Peggy Gerba, F. Wuytack, Richard Deth (1973)
Factors controlling cytoplasmic Ca 2+ concentration.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 265 867
J. Fain (1973)
Biochemical aspects of drug and hormone action on adipose tissue.Pharmacological reviews, 25 1
H. Rasmussen (1970)
Cell Communication, Calcium Ion, and Cyclic Adenosine MonophosphateScience, 170
B. Alm, S. Efendić, H. Löw (1970)
Effect of Lipolytic and Antilipolytic Agents on the Uptake of 47 Calcium into Rat Adipose Tissue In VitroHormone and Metabolic Research, 2
S. Keppens, J. Vandenheede, H. Wulf (1977)
On the role of calcium as second messenger in liver for the hormonally induced activation of glycogen phosphorylase.Biochimica et biophysica acta, 496 2
T. Yen, J. Steinmetz (2009)
Lipolysis of Genetically Obese and/or Hyperglycemic Mice with Reference to Insulin Response of Adipose TissueHormone and Metabolic Research, 4
(1977)
Effect of lipolytic agents on calcium uptake in the epididymal adipose tissue of obesehyperglycemic mice and their lean littermates
J. Winand, J. Christophe (1976)
Proceedings: Effect of preincubation on the metabolism of (U-14C) glucose and (3H)H2O by the epididymal adipose tissue of obese-hyperglycemic (ob/ob) Bar Harbor mice.Archives internationales de physiologie et de biochimie, 84 1
(1974)
Locali - zation of calcium in the smooth endoplasmic reticulum of rat isolated fat cells
J. Khoo, D. Steinberg, B. Thompson, S. Mayer (1973)
Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen synthase.The Journal of biological chemistry, 248 11
B. Hellman (1978)
Calcium and pancreatic β-cell function: 3. Validity of the La3+-wash technique for discriminating between superficial and intracellular 45CaBiochimica et Biophysica Acta, 540
(1976)
Effect of preincubation on the metabolism of [ U - ' ' ' C ] glucose and [ ' H ] H 2 O by the epididy - mal adipose tissue of obese - hyperglycemic ( ob / ob ) Bar Harbor mice
(1967)
Métabolisme in vitro du tissu adipeux . IV . Relations entre les espaces aqueux du tissu adipeux épididymaire du rat et l ' albumine sérique
(1957)
Eine enzymatische Methode zur Bestimmung yon Glycerol
Schimmel Rj (1978)
Calcium antagonists and lipolysis in isolated rat epididymal adipocytes: effects of tetracaine, manganese, cobaltous and lanthanum ions and D600.Hormone and Metabolic Research, 10
James Cohen, Alan Johnson (1991)
Differential effects of laminin and merosin on neurite outgrowth by developing retinal ganglion cellsJournal of Cell Science, 1991
125 16 16 6 6 J. P. Dehaye J. Winand P. Poloczek J. Christophe Department of Biochemistry, Medical School U. L. B. Brussels Belgium Summary In the epididymal adipose tissue of lean (+/+) C57 BL/6J mice deprived of calcium by ethy-leneglycol-bis-( β -aminoethylether) N,N′-tetraacetic acid (EGTA) treatment, corticotrophin-(1-24)-tetracosapeptide (ACTH)-stimulated lipolysis was abolished and peak levels of adenosine 3′,5′-cyclic monophosphate (cyclic AMP 1 ) were reduced by 80%. Calcium omission was less effective on isoproterenol-stimulated lipolysis and was ineffective on theophylline- or dibutyryl cyclic AMP-stimulated lipolysis. All EGTA effects were reversible. Lipolytic agents stimulated the net uptake of 45 Ca. This effect was inhibited by 2,4-dinitrophenol. The 45 Ca accumulated in response to lipolytic agents was largely La 3+ -nondisplaceable and was released with a half-life of 13 minutes under EGTA treatment. These results suggest that the mechanism promoting 45 Ca uptake in response to lipolytic agents was beyond cyclic AMP production in the adipose tissue of lean mice, but independent of free fatty acid release. In turn, intracellular as well as extracellular calcium facilitated maximal rates of lipolysis. In the adipose tissue of obese-hyperglycaemic (ob/ob) mice, the response to the lipolytic agents of glycerol release and cyclic AMP levels was reduced by 65% and 45 Ca uptake was not stimulated. A 1–2 hour preincubation of adipose tissue increased markedly the effect upon lipolysis and 45 Ca uptake, but not that of peak cyclic AMP levels of isoproterenol. It is concluded that the adipose tissue of ob/ob mice displayed a reversible impairment of 45 Ca uptake in response to lipolytic agents.
Diabetologia – Springer Journals
Published: Jun 1, 1979
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.