Clin Transl Oncol (2017) 19:1161–1167 DOI 10.1007/s12094-017-1655-9 RESEARCH AR TIC L E Reduced late urinary toxicity with high-dose intensity-modulated radiotherapy using intra-prostate ﬁducial markers for localized prostate cancer 1 1 1 1 1 • • • • • A. Zapatero M. Roch D. Bu¨chser P. Castro L. Ferna´ndez-Banda 1 1 1 1 1 • • • • G. Pozo O. Lin˜a´n C. Martin de Vidales A. Cruz-Conde F. Garcı´a-Vicente Received: 7 February 2017 / Accepted: 24 March 2017 / Published online: 3 April 2017 Federacio ´ n de Sociedades Espan ˜ olas de Oncologı ´a (FESEO) 2017 Abstract complications (HR 2.464, p = 0.002) and of hematuria Background/purpose To evaluate the impact of intensity- (HR 5.196, p \ 0.001). modulated radiotherapy (IMRT) with intra-prostate ﬁducial Conclusion Compared with 3DCRT, high-dose IMRT/ markers image-guided radiotherapy (IGRT) on the inci- IGRT is associated with a lower rate of late urinary com- dence of late urinary toxicity compared to 3D conformal plications in spite of higher radiation dose. radiotherapy (3DCRT) for patients with prostate cancer (PC). Keywords Prostate cancer IMRT 3DCRT Urinary Methods and materials We selected 733 consecutive toxicity Late toxicity Hematuria patients with localized PC
Clinical and Translational Oncology – Springer Journals
Published: Apr 3, 2017
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