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Supplement 2/11 Innsbruck, June 16–18, 2011 Th e PneumoUpdate Team: Christian M. Kähler, Wolfgang Hilbe, Herbert Jamnig, Ralf Ewert, Th omas Geiser memo Suppl 2/11 III Abstracts O02 Abstracts Endothelial progenitor cells and the endothelin system O01 S. Desole, F. Albrecht, H. Vogelsinger, K. Cima, C. M. Kähler A short splice variant of the tumour Department of Internal Medicine I – Pneumology, Medical suppressor gene CYLD induces University of Innsbruck, Innsbruck, Austria hyperactive T cells which are responsible Emerging evidence indicates that bone-marrow-de- for a augmented allergic airway disease rived endothelial progenitor cells (EPC) might play a key role in the formation of new vessels. Endothelin-1 (ET-1) modu- 1 2 1 1 S. Reuter , M. Becker , N. Dehzad , H. Martin , lates diff erent stages of neovascularisation, e.g. proliferation, 3 2 1 1 A. Waisman , M. Stassen , R. Buhl , C. Taube migration, invasion, protease production and changes in Department of Pulmonary Medicine, Medical Clinic III, morphogenesis of endothelial cells. We investigated a poten- University of Mainz, Mainz, Germany tial link between the ET system and EPC. Institute of Immunology, University of Mainz, Mainz, For all experiments ex vivo generated, characterised Germany and cultivated
memo - Magazine of European Medical Oncology – Springer Journals
Published: Jun 21, 2011
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